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    FCY2 purine-cytosine permease [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856783, updated on 28-Oct-2024

    Summary

    Official Symbol
    FCY2
    Official Full Name
    purine-cytosine permease
    Primary source
    SGD:S000000858
    Locus tag
    YER056C
    See related
    AllianceGenome:SGD:S000000858; FungiDB:YER056C; VEuPathDB:YER056C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    BRA7
    Summary
    Enables cytidine transmembrane transporter activity and nucleobase transmembrane transporter activity. Involved in cytidine transport; cytosine transport; and purine-containing compound transmembrane transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

    See FCY2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (266512..268113, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Gip2p Neighboring gene ATP phosphoribosyltransferase Neighboring gene ribosomal 60S subunit protein L34A Neighboring gene putative isoleucine biosynthesis protein HMF1

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Process Evidence Code Pubs
    involved_in cytidine transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cytidine transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cytosine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cytosine transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in purine-containing compound transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    purine-cytosine permease
    NP_010976.1
    • Purine-cytosine permease; mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation; relative distribution to the vacuole increases upon DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      266512..268113 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178947.1NP_010976.1  TPA: purine-cytosine permease [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010976.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLV9, P17064
      UniProtKB/TrEMBL
      C8Z761
      Conserved Domains (1) summary
      COG1457
      Location:65533
      CodB; Purine-cytosine permease or related protein [Nucleotide transport and metabolism]