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    VHA-A vacuolar ATP synthase subunit A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844228, updated on 18-Sep-2024

    Summary

    Official Symbol
    VHA-A
    Official Full Name
    vacuolar ATP synthase subunit A
    Primary source
    TAIR:AT1G78900
    Locus tag
    AT1G78900
    See related
    Araport:AT1G78900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    vacuolar ATP synthase subunit A
    Summary
    Encodes catalytic subunit A of the vacuolar ATP synthase. Mutants are devoid of vacuolar ATPase activity as subunit A is encoded only by this gene and show strong defects in male gametophyte development and in Golgi stack morphology.
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    Genomic context

    See VHA-A in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    20
    Sequence:
    Chromosome: 1; NC_003070.9 (29660088..29665078)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Ubiquitin-specific protease family C19-related protein Neighboring gene uncharacterized protein Neighboring gene Reticulon family protein Neighboring gene Pseudouridine synthase family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene ncRNA

    Bibliography

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001036222.3
    NM_106539.6

    Gene Ontology Provided by TAIR

    General protein information

    Preferred Names
    vacuolar ATP synthase subunit A
    NP_001031299.1
    • vacuolar ATP synthase subunit A (VHA-A); FUNCTIONS IN: hydrogen ion transporting ATP synthase activity, rotational mechanism, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances, proton-transporting ATPase activity, rotational mechanism, ATP binding; INVOLVED IN: response to salt stress, proton transport, Golgi organization, pollen development; LOCATED IN: in 8 components; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, alpha/beta subunit, nucleotide-binding domain, active site (InterPro:IPR020003), ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal (InterPro:IPR000793), ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal (InterPro:IPR004100), ATPase, F1/A1 complex, alpha/beta subunit, N-terminal (InterPro:IPR018118), ATPase, alpha/beta subunit, nucleotide-binding domain (InterPro:IPR000194), ATPase, V1 complex, subunit A (InterPro:IPR005725); BEST Arabidopsis thaliana protein match is: ATP synthase alpha/beta family protein (TAIR:AT5G08670.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_178011.1
    • vacuolar ATP synthase subunit A (VHA-A); FUNCTIONS IN: hydrogen ion transporting ATP synthase activity, rotational mechanism, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances, proton-transporting ATPase activity, rotational mechanism, ATP binding; INVOLVED IN: response to salt stress, proton transport, Golgi organization, pollen development; LOCATED IN: in 8 components; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal (InterPro:IPR000793), ATPase, alpha/beta subunit, nucleotide-binding domain, active site (InterPro:IPR020003), ATPase, F1/A1 complex, alpha/beta subunit, N-terminal (InterPro:IPR018118), ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal (InterPro:IPR004100), ATPase, V1 complex, subunit A (InterPro:IPR005725), ATPase, alpha/beta subunit, nucleotide-binding domain (InterPro:IPR000194); BEST Arabidopsis thaliana protein match is: ATP synthase alpha/beta family protein (TAIR:AT5G08670.1); Has 40508 Blast hits to 38748 proteins in 9967 species: Archae - 874; Bacteria - 22679; Metazoa - 1366; Fungi - 853; Plants - 8095; Viruses - 0; Other Eukaryotes - 6641 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      29660088..29665078
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106539.6NP_178011.1  vacuolar ATP synthase subunit A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178011.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23654
      UniProtKB/TrEMBL
      A0A178W720, A0A384LM33, Q0WLF6
      Conserved Domains (1) summary
      TIGR01042
      Location:20611
      V-ATPase_V1_A; V-type (H+)-ATPase V1, A subunit
    2. NM_001036222.3NP_001031299.1  vacuolar ATP synthase subunit A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031299.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23654
      UniProtKB/TrEMBL
      A0A178W720, A0A384LM33, Q0WLF6
      Conserved Domains (1) summary
      TIGR01042
      Location:20611
      V-ATPase_V1_A; V-type (H+)-ATPase V1, A subunit