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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850876, updated on 3-Nov-2024

    Summary

    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000004169
    Locus tag
    YLR179C
    See related
    AllianceGenome:SGD:S000004169; FungiDB:YLR179C; VEuPathDB:YLR179C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable peptidase inhibitor activity and phospholipid binding activity. Predicted to be involved in regulation of Ras protein signal transduction and regulation of proteolysis. Located in cytoplasm. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to several human genes including PEBP1 (phosphatidylethanolamine binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (514108..514713, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Tfs1p Neighboring gene methionine adenosyltransferase SAM1 Neighboring gene Vta1p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables peptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in regulation of Ras protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    NP_013280.1
    • hypothetical protein with similarity to Tfs1p; transcription is activated by paralogous proteins Yrm1p and Yrr1p along with proteins involved in multidrug resistance; GFP-tagged protein localizes to the cytoplasm and nucleus

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      514108..514713 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182066.1NP_013280.1  TPA: uncharacterized protein YLR179C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013280.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VYI3, Q06252
      UniProtKB/TrEMBL
      A7A170, G2WJ12, N1NZD3
      Conserved Domains (1) summary
      cd00866
      Location:30190
      PEBP_euk; PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in eukaryotes