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    Enkd1 enkurin domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291975, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Enkd1provided by RGD
    Official Full Name
    enkurin domain containing 1provided by RGD
    Primary source
    RGD:1307357
    See related
    AllianceGenome:RGD:1307357
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307357
    Summary
    Predicted to be located in ciliary base and microtubule cytoskeleton. Predicted to be active in cytoplasmic microtubule. Orthologous to human ENKD1 (enkurin domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 64.0), Kidney (RPKM 34.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Enkd1 in Genome Data Viewer
    Location:
    19q12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (50501963..50506447, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (33592074..33596552, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (37670624..37675101, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene CCCTC-binding factor like 2 Neighboring gene CCCTC-binding factor Neighboring gene capping protein regulator and myosin 1 linker 2 Neighboring gene similar to human chromosome 16 open reading frame 86 Neighboring gene par-6 family cell polarity regulator alpha Neighboring gene ACD, shelterin complex subunit and telomerase recruitment factor Neighboring gene Gfo/Idh/MocA-like oxidoreductase domain containing 2 Neighboring gene small nuclear ribonucleoprotein polypeptide G, pseudogene 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis. Fong KW, et al. J Cell Sci, 2013 Feb 1. PMID 23264731, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables alpha-tubulin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in establishment of mitotic spindle orientation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in non-motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in 9+0 non-motile cilium ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in ciliary base ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytoplasmic microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasmic microtubule ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    enkurin domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106180.1 → NP_001099650.1  enkurin domain-containing protein 1

      See identical proteins and their annotated locations for NP_001099650.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473972
      UniProtKB/TrEMBL
      A6IYS0, D4A243
      Conserved Domains (1) summary
      pfam13864
      Location:243 → 337
      Enkurin; Calmodulin-binding

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      50501963..50506447 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006255476.5 → XP_006255538.1  enkurin domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006255538.1

      UniProtKB/TrEMBL
      A6IYS0, D4A243
      Conserved Domains (1) summary
      pfam13864
      Location:243 → 337
      Enkurin; Calmodulin-binding

    2. XM_006255478.5 → XP_006255540.1  enkurin domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006255540.1

      UniProtKB/TrEMBL
      A6IYS0, D4A243
      Conserved Domains (1) summary
      pfam13864
      Location:243 → 337
      Enkurin; Calmodulin-binding

    3. XM_006255477.5 → XP_006255539.1  enkurin domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006255539.1

      UniProtKB/TrEMBL
      A6IYS0, D4A243
      Conserved Domains (1) summary
      pfam13864
      Location:243 → 337
      Enkurin; Calmodulin-binding

    4. XM_039097617.2 → XP_038953545.1  enkurin domain-containing protein 1 isoform X3

    5. XM_063277925.1 → XP_063133995.1  enkurin domain-containing protein 1 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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