U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Higd1b HIG1 hypoxia inducible domain family, member 1B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287738, updated on 10-Jul-2024

    Summary

    Official Symbol
    Higd1bprovided by RGD
    Official Full Name
    HIG1 hypoxia inducible domain family, member 1Bprovided by RGD
    Primary source
    RGD:1306907
    See related
    EnsemblRapid:ENSRNOG00000081879 AllianceGenome:RGD:1306907
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306907
    Summary
    Predicted to be involved in mitochondrial respirasome assembly. Predicted to be integral component of membrane. Predicted to be active in mitochondrion. Orthologous to human HIGD1B (HIG1 hypoxia inducible domain family member 1B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Lung (RPKM 99.3), Heart (RPKM 24.9) and 6 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Higd1b in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (88302284..88304558)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (87798864..87804459)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (90929362..90931639)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095185 Neighboring gene ADAM metallopeptidase domain 11 Neighboring gene gap junction protein, gamma 1 Neighboring gene elongation factor Tu GTP binding domain containing 2 Neighboring gene coiled-coil domain containing 103 Neighboring gene family with sequence similarity 187, member A

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in mitochondrial respirasome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    HIG1 domain family member 1B
    Names
    HIG1 domain family, member 1B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105844.1NP_001099314.1  HIG1 domain family member 1B

      See identical proteins and their annotated locations for NP_001099314.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A6HJM9
      Related
      ENSRNOP00000104141.1, ENSRNOT00000164451.1
      Conserved Domains (1) summary
      pfam04588
      Location:2979
      HIG_1_N; Hypoxia induced protein conserved region

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      88302284..88304558
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008768263.3XP_008766485.1  HIG1 domain family member 1B isoform X1

      See identical proteins and their annotated locations for XP_008766485.1

      UniProtKB/TrEMBL
      A6HJM9
      Conserved Domains (1) summary
      pfam04588
      Location:2979
      HIG_1_N; Hypoxia induced protein conserved region
    2. XM_008768265.3XP_008766487.1  HIG1 domain family member 1B isoform X1

      See identical proteins and their annotated locations for XP_008766487.1

      UniProtKB/TrEMBL
      A6HJM9
      Conserved Domains (1) summary
      pfam04588
      Location:2979
      HIG_1_N; Hypoxia induced protein conserved region
    3. XM_008768264.4XP_008766486.1  HIG1 domain family member 1B isoform X1

      See identical proteins and their annotated locations for XP_008766486.1

      UniProtKB/TrEMBL
      A6HJM9
      Conserved Domains (1) summary
      pfam04588
      Location:2979
      HIG_1_N; Hypoxia induced protein conserved region