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    Trappc8 trafficking protein particle complex subunit 8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291750, updated on 10-Oct-2024

    Summary

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    Symbol
    Trappc8provided by RGD
    Full Name
    trafficking protein particle complex subunit 8provided by RGD
    Primary source
    RGD:1309102
    See related
    EnsemblRapid:ENSRNOG00000022202 AllianceGenome:RGD:1309102
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309102
    Summary
    Predicted to be involved in several processes, including autophagy of peroxisome; endoplasmic reticulum to Golgi vesicle-mediated transport; and protein localization to phagophore assembly site. Predicted to be part of TRAPPIII protein complex. Predicted to be active in cytoplasmic vesicle and phagophore assembly site. Orthologous to human TRAPPC8 (trafficking protein particle complex subunit 8). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 94.6), Lung (RPKM 88.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Trappc8 in Genome Data Viewer
    Location:
    18p12
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (12378825..12455364, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (12103874..12180422, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (15298673..15375034)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene importin 5, pseudogene 1 Neighboring gene uncharacterized LOC120098272 Neighboring gene small ribosomal subunit protein eS26-like Neighboring gene histone-lysine N-methyltransferase EZH2-like Neighboring gene elongation factor 2-like Neighboring gene eukaryotic translation elongation factor 2, pseudogene 4 Neighboring gene ring finger protein 125

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking. Scrivens PJ, et al. Mol Biol Cell, 2011 Jun 15. PMID 21525244, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in collagen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in collagen biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of TRAPP complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of TRAPPIII protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    trafficking protein particle complex subunit 8
    Names
    trafficking protein particle complex 8
    trafficking protein particle complex subunit 8-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106160.1 → NP_001099630.1  trafficking protein particle complex subunit 8

      See identical proteins and their annotated locations for NP_001099630.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473974
      UniProtKB/TrEMBL
      A6J2G6, F1M9W9
      Related
      ENSRNOP00000092280.2, ENSRNOT00000118017.2
      Conserved Domains (1) summary
      pfam12739
      Location:158 → 604
      TRAPPC-Trs85; ER-Golgi trafficking TRAPP I complex 85 kDa subunit

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      12378825..12455364 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277260.1 → XP_063133330.1  trafficking protein particle complex subunit 8 isoform X3

    2. XM_063277259.1 → XP_063133329.1  trafficking protein particle complex subunit 8 isoform X2

    3. XM_063277258.1 → XP_063133328.1  trafficking protein particle complex subunit 8 isoform X1

    4. XM_063277261.1 → XP_063133331.1  trafficking protein particle complex subunit 8 isoform X6

    5. XM_006254462.5 → XP_006254524.1  trafficking protein particle complex subunit 8 isoform X5

      UniProtKB/TrEMBL
      F1M9W9
      Conserved Domains (1) summary
      pfam12739
      Location:158 → 585
      TRAPPC-Trs85; ER-Golgi trafficking TRAPP I complex 85 kDa subunit

    6. XM_006254461.5 → XP_006254523.1  trafficking protein particle complex subunit 8 isoform X4

      UniProtKB/TrEMBL
      F1M9W9
      Conserved Domains (1) summary
      pfam12739
      Location:158 → 586
      TRAPPC-Trs85; ER-Golgi trafficking TRAPP I complex 85 kDa subunit

    7. XM_039096738.2 → XP_038952666.1  trafficking protein particle complex subunit 8 isoform X8

      UniProtKB/TrEMBL
      A0A8I6AGT6
      Conserved Domains (1) summary
      pfam12739
      Location:10 → 417
      TRAPPC-Trs85; ER-Golgi trafficking TRAPP I complex 85 kDa subunit

    8. XM_063277262.1 → XP_063133332.1  trafficking protein particle complex subunit 8 isoform X7

    9. XM_063277263.1 → XP_063133333.1  trafficking protein particle complex subunit 8 isoform X9

    Nucleotide Protein Strain
    Heading Accession and Version

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