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    Myoz3 myozenin 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689274, updated on 17-Aug-2024

    Summary

    Official Symbol
    Myoz3provided by RGD
    Official Full Name
    myozenin 3provided by RGD
    Primary source
    RGD:1594778
    See related
    EnsemblRapid:ENSRNOG00000087346 AllianceGenome:RGD:1594778
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable FATZ binding activity; actin binding activity; and telethonin binding activity. Predicted to be active in Z disc and actin cytoskeleton. Orthologous to human MYOZ3 (myozenin 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 361.7) See more
    Orthologs
    NEW
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    Genomic context

    Location:
    18q12.1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (56296565..56316582, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (54026133..54046151, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (55840535..55861217, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 3 Neighboring gene dynactin subunit 4 Neighboring gene RNA binding motif protein 22 Neighboring gene synaptopodin Neighboring gene uncharacterized LOC120098275

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables FATZ binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables actin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables telethonin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in modification of dendritic spine IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in Z disc IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Z disc ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001400829.1NP_001387758.1  myozenin-3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      A0A0H2UHR2
      Related
      ENSRNOP00000025989.3, ENSRNOT00000025989.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      56296565..56316582 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)