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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851709, updated on 2-Nov-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000002538
    Locus tag
    YDR131C
    See related
    AllianceGenome:SGD:S000002538; FungiDB:YDR131C; VEuPathDB:YDR131C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables ubiquitin protein ligase binding activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Part of SCF ubiquitin ligase complex. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (716790..718460, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene fimbrin Neighboring gene Fin1p Neighboring gene Mrx16p Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deletion of autophagy related, ATG1 and F-box motif encoding YDR131C, together, lead to synthetic growth defects and flocculation behavior in Saccharomyces cerevisiae. Shoket H, et al. J Biochem Mol Toxicol, 2022 Jul. PMID 35385166
    2. Genetic interaction between F-box motif encoding YDR131C and retrograde signaling-related RTG1 regulates the stress response and apoptosis in Saccharomyces cerevisiae. Shoket H, et al. J Biochem Mol Toxicol, 2021 Oct. PMID 34309121
    3. A longevity protein, Lag2, interacts with SCF complex and regulates SCF function. Liu Y, et al. EMBO J, 2009 Nov 4. PMID 19763088, Free PMC Article
    4. SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis. Willems AR, et al. Philos Trans R Soc Lond B Biol Sci, 1999 Sep 29. PMID 10582239, Free PMC Article
    5. Identification of F-box proteins that are involved in resistance to methylmercury in Saccharomyces cerevisiae. Hwang GW, et al. FEBS Lett, 2006 Dec 22. PMID 17141224

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ubiquitin protein ligase binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SCF ubiquitin ligase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_010416.1
    • F-box protein subunit of SCF ubiquitin ligase complex; substrate-specific adaptor subunit that recruits substrates to a core ubiquitination complex

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      716790..718460 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180439.1 → NP_010416.1  TPA: uncharacterized protein YDR131C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010416.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSB7, Q03899
      UniProtKB/TrEMBL
      A6ZY92, B3LGE6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03899.1

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