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    Rec114 REC114 meiotic recombination protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300751, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Rec114provided by RGD
    Official Full Name
    REC114 meiotic recombination proteinprovided by RGD
    Primary source
    RGD:1311874
    See related
    EnsemblRapid:ENSRNOG00000009332 AllianceGenome:RGD:1311874
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311874
    Summary
    Predicted to be involved in meiotic DNA double-strand break formation; oogenesis; and spermatogenesis. Predicted to be located in chromosome. Orthologous to human REC114 (REC114 meiotic recombination protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 395.6), Lung (RPKM 313.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rec114 in Genome Data Viewer
    Location:
    8q24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (67959181..68117296, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (59063352..59221439, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (63445644..63533645, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene inhibitory synaptic factor 1 Neighboring gene Cd276 molecule Neighboring gene neuroplastin Neighboring gene nucleophosmin-like Neighboring gene hyperpolarization activated cyclic nucleotide-gated potassium channel 4 Neighboring gene neogenin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in meiotic DNA double-strand break formation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in oogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    meiotic recombination protein REC114

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106825.2 → NP_001100295.1  meiotic recombination protein REC114 isoform 2

      See identical proteins and their annotated locations for NP_001100295.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6J513
      Conserved Domains (1) summary
      pfam15165
      Location:20 → 254
      REC114-like; Meiotic recombination protein REC114-like

    2. NM_001433278.1 → NP_001420207.1  meiotic recombination protein REC114 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      D3ZB61

    3. NM_001433279.1 → NP_001420208.1  meiotic recombination protein REC114 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      67959181..68117296 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081093.2 → XP_038937021.1  meiotic recombination protein REC114 isoform X5

      Conserved Domains (1) summary
      pfam15165
      Location:1 → 155
      REC114-like; Meiotic recombination protein REC114-like

    2. XM_006243160.5 → XP_006243222.1  meiotic recombination protein REC114 isoform X4

      Conserved Domains (1) summary
      pfam15165
      Location:20 → 223
      REC114-like; Meiotic recombination protein REC114-like

    3. XM_063265122.1 → XP_063121192.1  meiotic recombination protein REC114 isoform X3

    4. XM_006243158.5 → XP_006243220.1  meiotic recombination protein REC114 isoform X2

      Related
      ENSRNOP00000101309.1, ENSRNOT00000162667.1
      Conserved Domains (1) summary
      pfam15165
      Location:20 → 242
      REC114-like; Meiotic recombination protein REC114-like

    5. XM_006243157.5 → XP_006243219.1  meiotic recombination protein REC114 isoform X1

      Conserved Domains (1) summary
      pfam15165
      Location:20 → 271
      REC114-like; Meiotic recombination protein REC114-like

    6. XM_039081092.2 → XP_038937020.1  meiotic recombination protein REC114 isoform X4

      Conserved Domains (1) summary
      pfam15165
      Location:20 → 223
      REC114-like; Meiotic recombination protein REC114-like
    Nucleotide Protein Strain
    Heading Accession and Version

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