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    Eif1b eukaryotic translation initiation factor 1B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 301068, updated on 10-Jul-2024

    Summary

    Official Symbol
    Eif1bprovided by RGD
    Official Full Name
    eukaryotic translation initiation factor 1Bprovided by RGD
    Primary source
    RGD:1309241
    See related
    EnsemblRapid:ENSRNOG00000018848 AllianceGenome:RGD:1309241
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309241
    Summary
    Predicted to enable ribosomal small subunit binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic 43S preinitiation complex. Orthologous to human EIF1B (eukaryotic translation initiation factor 1B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 196.3), Testes (RPKM 187.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Eif1b in Genome Data Viewer
    Location:
    8q32
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (129080497..129083772)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (120203561..120206176)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (129158112..129160726)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene myosin VIIA and Rab interacting protein Neighboring gene uncharacterized LOC108351802 Neighboring gene uncharacterized LOC120094297 Neighboring gene transfer RNA proline (anticodon AGG) 29 Neighboring gene small ribosomal subunit protein uS19-like Neighboring gene ferritin light chain 1, pseudogene 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribosomal small subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of eukaryotic 43S preinitiation complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 1b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106867.1NP_001100337.1  eukaryotic translation initiation factor 1b

      See identical proteins and their annotated locations for NP_001100337.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473954
      UniProtKB/TrEMBL
      A0A8I6AB39, B5DFN1
      Related
      ENSRNOP00000025615.6, ENSRNOT00000025615.9
      Conserved Domains (1) summary
      cl00229
      Location:4113
      eIF1_SUI1_like; Eukaryotic initiation factor 1 and related proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      129080497..129083772
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265305.1XP_063121375.1  eukaryotic translation initiation factor 1b isoform X1