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    Ipo11 importin 11 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310056, updated on 10-Jul-2024

    Summary

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    Official Symbol
    Ipo11provided by RGD
    Official Full Name
    importin 11provided by RGD
    Primary source
    RGD:1311133
    See related
    EnsemblRapid:ENSRNOG00000062438 AllianceGenome:RGD:1311133
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable nuclear import signal receptor activity. Predicted to act upstream of or within ribosomal protein import into nucleus. Predicted to be located in nucleoplasm. Orthologous to human IPO11 (importin 11). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 180.7), Thymus (RPKM 126.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ipo11 in Genome Data Viewer
    Location:
    2q13
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (39903316..40076485, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (38169688..38342929, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (37952982..38120451, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102556361 Neighboring gene uncharacterized LOC134485592 Neighboring gene leucine rich repeat containing 70 Neighboring gene DIM1 rRNA methyltransferase and ribosome maturation factor Neighboring gene uncharacterized LOC134485593 Neighboring gene kinesin family member 2A Neighboring gene ribosomal protein L23A like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11. Plafker SM, et al. Mol Cell Biol, 2002 Feb. PMID 11809816, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    importin-11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      39903316..40076485 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282684.1 → XP_063138754.1  importin-11 isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZYN9

    2. XM_063282685.1 → XP_063138755.1  importin-11 isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZYN9

    3. XM_063282683.1 → XP_063138753.1  importin-11 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZYN9
      Related
      ENSRNOP00000096542.2, ENSRNOT00000094263.2

    4. XM_063282682.1 → XP_063138752.1  importin-11 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZYN9
      Related
      ENSRNOP00000101394.1, ENSRNOT00000167605.1

    5. XM_063282686.1 → XP_063138756.1  importin-11 isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZYN9

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001107649.1: Suppressed sequence

      Description
      NM_001107649.1: This RefSeq was temporarily suppressed because currently available homology data do not support the shorter protein that it encodes.
    Nucleotide Protein Strain
    Heading Accession and Version

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