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    RRN10 Rrn10p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852256, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RRN10
    Official Full Name
    Rrn10p
    Primary source
    SGD:S000000121
    Locus tag
    YBL025W
    See related
    AllianceGenome:SGD:S000000121; FungiDB:YBL025W; VEuPathDB:YBL025W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables RNA polymerase I cis-regulatory region sequence-specific DNA binding activity and RNA polymerase I general transcription initiation factor activity. Involved in nucleolar large rRNA transcription by RNA polymerase I. Located in nucleolus. Part of RNA polymerase I upstream activating factor complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RRN10 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (171481..171918)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L19B Neighboring gene Sm-like protein LSM2 Neighboring gene tRNA (cytosine-C5-)-methyltransferase Neighboring gene MCM DNA helicase complex subunit MCM2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Construction of a Saccharomyces cerevisiae strain with a high level of RNA. Chuwattanakul V, et al. J Biosci Bioeng, 2011 Jul. PMID 21571588
    2. Increased transcription of NOP15, involved in ribosome biogenesis in Saccharomyces cerevisiae, enhances the production yield of RNA as a source of nucleotide seasoning. Chuwattanakul V, et al. J Biosci Bioeng, 2012 Jul. PMID 22608550
    3. Increased transcription of RPL40A and RPL40B is important for the improvement of RNA production in Saccharomyces cerevisiae. Khatun F, et al. J Biosci Bioeng, 2013 Oct. PMID 23669742
    4. Interaction of TATA-binding protein with upstream activation factor is required for activated transcription of ribosomal DNA by RNA polymerase I in Saccharomyces cerevisiae in vivo. Steffan JS, et al. Mol Cell Biol, 1998 Jul. PMID 9632758, Free PMC Article
    5. Histones H3 and H4 are components of upstream activation factor required for the high-level transcription of yeast rDNA by RNA polymerase I. Keener J, et al. Proc Natl Acad Sci U S A, 1997 Dec 9. PMID 9391047, Free PMC Article

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA polymerase I cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase I cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA polymerase I cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase I general transcription initiation factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleolar large rRNA transcription by RNA polymerase I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nucleolar large rRNA transcription by RNA polymerase I IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in nucleolar large rRNA transcription by RNA polymerase I IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nucleolar large rRNA transcription by RNA polymerase I IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase I upstream activating factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase I upstream activating factor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase I upstream activating factor complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Rrn10p
    NP_009528.1
    • Protein involved in promoting high level transcription of rDNA; subunit of UAF (upstream activation factor) for RNA polymerase I

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      171481..171918
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178265.1 → NP_009528.1  TPA: Rrn10p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009528.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VPX5, P38204
      UniProtKB/TrEMBL
      A6ZKS3, B3LNG2, C7GX85, C8Z3X1, G2W8Y4, N1P8T2
      Conserved Domains (1) summary
      pfam05234
      Location:1 → 120
      UAF_Rrn10; UAF complex subunit Rrn10
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38204.1

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