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    TOG1 Tog1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856933, updated on 28-Oct-2024

    Summary

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    Official Symbol
    TOG1
    Official Full Name
    Tog1p
    Primary source
    SGD:S000000986
    Locus tag
    YER184C
    See related
    AllianceGenome:SGD:S000000986; FungiDB:YER184C; VEuPathDB:YER184C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

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    See TOG1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (556296..558680, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Fmp10p Neighboring gene 5-formyltetrahydrofolate cyclo-ligase Neighboring gene Pug1p Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The novel zinc cluster regulator Tog1 plays important roles in oleate utilization and oxidative stress response in Saccharomyces cerevisiae. Thepnok P, et al. Biochem Biophys Res Commun, 2014 Aug 8. PMID 24998441
    2. Target of rapamycin complex 2-dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae. Bourgoint C, et al. J Biol Chem, 2018 Aug 3. PMID 29895620, Free PMC Article
    3. Phenotypic analysis of genes encoding yeast zinc cluster proteins. Akache B, et al. Nucleic Acids Res, 2001 May 15. PMID 11353088, Free PMC Article
    4. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Badis G, et al. Mol Cell, 2008 Dec 26. PMID 19111667, Free PMC Article
    5. Functional Analysis of Kinases and Transcription Factors in Saccharomyces cerevisiae Using an Integrated Overexpression Library. Youn JY, et al. G3 (Bethesda), 2017 Mar 10. PMID 28122947, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tog1p
    NP_011111.1
    • Transcriptional activator of oleate genes; regulates genes involved in fatty acid utilization; zinc cluster protein; deletion confers sensitivity to Calcufluor white, and prevents growth on glycerol or lactate as sole carbon source

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      556296..558680 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179074.1 → NP_011111.1  TPA: Tog1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011111.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DM93, P39961
      UniProtKB/TrEMBL
      C7GUZ2, G2WD71
      Conserved Domains (2) summary
      pfam00172
      Location:16 → 53
      Zn_clus; Fungal Zn(2)-Cys(6) binuclear cluster domain
      pfam04082
      Location:236 → 485
      Fungal_trans; Fungal specific transcription factor domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P39961.1

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