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    YIP5 Yip5p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852715, updated on 2-Nov-2024

    Summary

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    Official Symbol
    YIP5
    Official Full Name
    Yip5p
    Primary source
    SGD:S000003129
    Locus tag
    YGL161C
    See related
    AllianceGenome:SGD:S000003129; FungiDB:YGL161C; VEuPathDB:YGL161C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables small GTPase binding activity. Predicted to be involved in vesicle-mediated transport. Located in Golgi apparatus. Orthologous to human YIPF1 (Yip1 domain family member 1) and YIPF2 (Yip1 domain family member 2). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See YIP5 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (199210..200142, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene DNA-dependent ATPase RAD54 Neighboring gene Sut1p Neighboring gene putative metalloreductase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Basic functional analysis of six unknown open reading frames from Saccharomyces cerevisiae: four from chromosome VII and two from chromosome XV. Pearson BM, et al. Yeast, 2002 Jan 30. PMID 11788967
    2. Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors. Calero M, et al. FEBS Lett, 2002 Mar 27. PMID 11943201
    3. Guanine nucleotide exchange factors (GEFs) have a critical but not exclusive role in organelle localization of Rab GTPases. Cabrera M, et al. J Biol Chem, 2013 Oct 4. PMID 23979137, Free PMC Article
    4. Intrinsic tethering activity of endosomal Rab proteins. Lo SY, et al. Nat Struct Mol Biol, 2011 Dec 11. PMID 22157956, Free PMC Article
    5. Predicting protein functions from redundancies in large-scale protein interaction networks. Samanta MP, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14566057, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables small GTPase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Yip5p
    NP_011354.3
    • Protein that interacts with Rab GTPases; localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      199210..200142 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181026.3 → NP_011354.3  TPA: Yip5p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011354.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTZ0, P53108
      UniProtKB/TrEMBL
      A6ZU24, B3LHL4, B5VIG6, C7GPP5, C8Z890, N1P6G5
      Conserved Domains (1) summary
      pfam04893
      Location:115 → 303
      Yip1; Yip1 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53108.1

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