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    Ccdc17 coiled-coil domain containing 17 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500528, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Ccdc17provided by RGD
    Official Full Name
    coiled-coil domain containing 17provided by RGD
    Primary source
    RGD:1598211
    See related
    EnsemblRapid:ENSRNOG00000023216 AllianceGenome:RGD:1598211
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human CCDC17 (coiled-coil domain containing 17). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Lung (RPKM 152.8), Kidney (RPKM 59.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccdc17 in Genome Data Viewer
    Location:
    5q35
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (135288799..135293339)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (130051158..130056676)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (135440276..135445794)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L7a, pseudogene 20 Neighboring gene intracisternal A particle-promoted polypeptide Neighboring gene transmembrane protein 69 Neighboring gene GC-rich promoter binding protein 1-like 1 Neighboring gene nuclear autoantigenic sperm protein Neighboring gene U6 spliceosomal RNA Neighboring gene aldo-keto reductase family 1 member A1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Impact of Genetic Variation in MicroRNA-binding Site on Susceptibility to Colorectal Cancer. Kang BW, et al. Anticancer Res, 2016 Jul. PMID 27354594
    2. Gene expression analysis in response to lung toxicants: I. Sequencing and microarray development. Shultz MA, et al. Am J Respir Cell Mol Biol, 2004 Mar. PMID 12947022
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 17

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014067.2 → NP_001014089.2  coiled-coil domain-containing protein 17

      Status: PROVISIONAL

      Source sequence(s)
      AA926261, BI292365, CF114603, CK476945, CO385240, CO398762
      UniProtKB/TrEMBL
      A0A0G2KAL0
      Conserved Domains (1) summary
      PRK03918
      Location:38 → 271
      PRK03918; chromosome segregation protein; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      135288799..135293339
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006238703.4 → XP_006238765.1  coiled-coil domain-containing protein 17 isoform X3

      UniProtKB/TrEMBL
      A0A0G2KAL0
      Conserved Domains (1) summary
      PRK03918
      Location:80 → 312
      PRK03918; chromosome segregation protein; Provisional

    2. XM_006238705.4 → XP_006238767.1  coiled-coil domain-containing protein 17 isoform X7

      UniProtKB/TrEMBL
      A0A0G2KAL0
      Conserved Domains (1) summary
      PRK03918
      Location:80 → 312
      PRK03918; chromosome segregation protein; Provisional

    3. XM_063288238.1 → XP_063144308.1  coiled-coil domain-containing protein 17 isoform X9

    4. XM_063288239.1 → XP_063144309.1  coiled-coil domain-containing protein 17 isoform X10

    5. XM_006238707.4 → XP_006238769.1  coiled-coil domain-containing protein 17 isoform X15

      UniProtKB/TrEMBL
      A0A0G2KAL0
      Related
      ENSRNOP00000075436.2, ENSRNOT00000090852.3
      Conserved Domains (1) summary
      COG1196
      Location:69 → 291
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    6. XM_063288240.1 → XP_063144310.1  coiled-coil domain-containing protein 17 isoform X11

    7. XM_063288241.1 → XP_063144311.1  coiled-coil domain-containing protein 17 isoform X13

    8. XM_039110594.2 → XP_038966522.1  coiled-coil domain-containing protein 17 isoform X14

    9. XM_006238702.4 → XP_006238764.1  coiled-coil domain-containing protein 17 isoform X1

      UniProtKB/TrEMBL
      A0A0G2KAL0
      Conserved Domains (1) summary
      PRK03918
      Location:80 → 312
      PRK03918; chromosome segregation protein; Provisional

    10. XM_006238706.4 → XP_006238768.1  coiled-coil domain-containing protein 17 isoform X8

      Conserved Domains (1) summary
      PRK03918
      Location:80 → 177
      PRK03918; chromosome segregation protein; Provisional

    11. XM_039110589.2 → XP_038966517.1  coiled-coil domain-containing protein 17 isoform X2

      UniProtKB/TrEMBL
      A0A0G2KAL0

    12. XM_006238704.4 → XP_006238766.1  coiled-coil domain-containing protein 17 isoform X4

      UniProtKB/TrEMBL
      A0A0G2KAL0, D3ZMQ6
      Related
      ENSRNOP00000034089.5, ENSRNOT00000034464.6
      Conserved Domains (1) summary
      COG1196
      Location:69 → 291
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    13. XM_039110590.2 → XP_038966518.1  coiled-coil domain-containing protein 17 isoform X5

      UniProtKB/TrEMBL
      A0A0G2KAL0

    14. XM_039110591.2 → XP_038966519.1  coiled-coil domain-containing protein 17 isoform X6

      UniProtKB/TrEMBL
      A0A0G2KAL0

    15. XM_039110592.1 → XP_038966520.1  coiled-coil domain-containing protein 17 isoform X12

    RNA

    1. XR_005504525.2 RNA Sequence

    2. XR_005504522.2 RNA Sequence

    3. XR_005504527.2 RNA Sequence

    4. XR_005504526.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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