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    TTC33 tetratricopeptide repeat domain 33 [ Homo sapiens (human) ]

    Gene ID: 23548, updated on 17-Sep-2024

    Summary

    Official Symbol
    TTC33provided by HGNC
    Official Full Name
    tetratricopeptide repeat domain 33provided by HGNC
    Primary source
    HGNC:HGNC:29959
    See related
    Ensembl:ENSG00000113638 AllianceGenome:HGNC:29959
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OSRF
    Expression
    Ubiquitous expression in brain (RPKM 7.4), thyroid (RPKM 4.0) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See TTC33 in Genome Data Viewer
    Location:
    5p13.1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (40711576..40755961, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (40967941..41012360, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (40711678..40756063, complement)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374737 Neighboring gene small nucleolar RNA SNORA63 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15982 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:40681035-40681562 Neighboring gene prostaglandin E receptor 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22503 Neighboring gene uncharacterized LOC124900968 Neighboring gene protein kinase AMP-activated catalytic subunit alpha 1 Neighboring gene HNF1 motif-containing MPRA enhancer 12 Neighboring gene small nucleolar RNA SNORA57

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    tetratricopeptide repeat protein 33
    Names
    TPR repeat protein 33
    osmosis responsive factor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012382.3NP_036514.1  tetratricopeptide repeat protein 33

      See identical proteins and their annotated locations for NP_036514.1

      Status: VALIDATED

      Source sequence(s)
      AC093264, AI174764, BC015701, BC036536, BE869916, BF509085, BM543635, BM689740, BQ922097, CR738110, DA518274, DA652008
      Consensus CDS
      CCDS3931.1
      UniProtKB/Swiss-Prot
      B2R6G0, O95105, Q6PID6
      Related
      ENSP00000338533.4, ENST00000337702.5
      Conserved Domains (2) summary
      sd00006
      Location:5987
      TPR; TPR repeat [structural motif]
      cl27017
      Location:71192
      YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      40711576..40755961 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011514003.4XP_011512305.1  tetratricopeptide repeat protein 33 isoform X1

      See identical proteins and their annotated locations for XP_011512305.1

      UniProtKB/Swiss-Prot
      B2R6G0, O95105, Q6PID6
      Conserved Domains (2) summary
      sd00006
      Location:5987
      TPR; TPR repeat [structural motif]
      cl27017
      Location:71192
      YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      40967941..41012360 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054352255.1XP_054208230.1  tetratricopeptide repeat protein 33 isoform X1

      UniProtKB/Swiss-Prot
      B2R6G0, O95105, Q6PID6