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    CRMA cardiomyocyte maturation associated lncRNA [ Homo sapiens (human) ]

    Gene ID: 253868, updated on 17-Sep-2024

    Summary

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    Official Symbol
    CRMAprovided by HGNC
    Official Full Name
    cardiomyocyte maturation associated lncRNAprovided by HGNC
    Primary source
    HGNC:HGNC:26393
    See related
    AllianceGenome:HGNC:26393
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CARMA; C20orf200; NCRNA00335; MIR1-1HG-AS1; C20orf166-AS1
    Expression
    Biased expression in heart (RPKM 4.0), prostate (RPKM 2.7) and 8 other tissues See more
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    Genomic context

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    See CRMA in Genome Data Viewer
    Location:
    20q13.33
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (62543070..62551561, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (64341587..64350086, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (61141438..61148768, complement)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18203 Neighboring gene uncharacterized LOC124904947 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61071135-61071640 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61071641-61072147 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61075123-61075623 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18204 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61086501-61087310 Neighboring gene uncharacterized LOC105376995 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:61147747-61148622 Neighboring gene MIR1-1 host gene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61153927-61154798 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61155669-61156540 Neighboring gene microRNA 1-1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61158329-61158846 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61158847-61159365 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61159366-61159883 Neighboring gene microRNA 133a-2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. The conserved long non-coding RNA CARMA regulates cardiomyocyte differentiation. Kay M, et al. Cardiovasc Res, 2022 Jul 27. PMID 34459880
    2. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Eeles RA, et al. Nat Genet, 2013 Apr. PMID 23535732, Free PMC Article
    3. Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease. Teixeira FR, et al. Biochem J, 2016 Oct 15. PMID 27503909, Free PMC Article
    4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The conserved long non-coding RNA CARMA regulates cardiomyocyte differentiation.
      Title: The conserved long non-coding RNA CARMA regulates cardiomyocyte differentiation.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • C20orf166 antisense RNA 1 (non-protein coding)
    • MIR1-1HG antisense RNA 1

    Clone Names

    • FLJ30313, MGC138143, DKFZp313D1938

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_033263.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC161429, AK056546, AL449263, AL832097, DA722400

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

      Range
      62543070..62551561 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060944.1 Alternate T2T-CHM13v2.0

      Range
      64341587..64350086 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_152757.1: Suppressed sequence

      Description
      NM_152757.1: This RefSeq was permanently suppressed because currently there is insufficient support for the protein.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials