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    SEMA4F ssemaphorin 4F [ Canis lupus familiaris (dog) ]

    Gene ID: 483098, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SEMA4Fprovided by VGNC
    Official Full Name
    ssemaphorin 4Fprovided by VGNC
    Primary source
    VGNC:VGNC:45997
    See related
    Ensembl:ENSCAFG00845017211
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 17
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (49341557..49373017, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (48121196..48152554, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (48983164..49014582, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (48355887..48387283, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (48420206..48451735, complement)

    Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene nucleoside diphosphate kinase A-like Neighboring gene eukaryotic initiation factor 4A-II-like Neighboring gene U6 spliceosomal RNA Neighboring gene meiosis 1 associated protein Neighboring gene vesicle-associated membrane protein 3-like Neighboring gene S-phase kinase-associated protein 1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chemorepellent activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables semaphorin receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of axon extension involved in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neural crest cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in semaphorin-plexin signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    semaphorin-4F

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051821.1 Reference ROS_Cfam_1.0

      Range
      49341557..49373017 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038691616.1 → XP_038547544.1  semaphorin-4F isoform X4

      UniProtKB/TrEMBL
      A0A8C0QBJ9, A0A8I3NZS3
      Conserved Domains (4) summary
      cd11261
      Location:30 → 489
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:490 → 541
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00096
      Location:548 → 553
      Ig; Ig strand A [structural motif]
      cl11960
      Location:548 → 627
      Ig; Immunoglobulin domain

    2. XM_038691614.1 → XP_038547542.1  semaphorin-4F isoform X2

      UniProtKB/TrEMBL
      A0A8C0QBD4, A0A8I3P073
      Related
      ENSCAFP00845024050.1, ENSCAFT00845030651.1
      Conserved Domains (5) summary
      smart00423
      Location:622 → 673
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:680 → 685
      Ig; Ig strand A [structural motif]
      cl11960
      Location:680 → 759
      Ig; Immunoglobulin domain
      cl15693
      Location:195 → 621
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    3. XM_038691615.1 → XP_038547543.1  semaphorin-4F isoform X3

      UniProtKB/TrEMBL
      A0A8I3P4M6, A0A8P0T4R6
      Conserved Domains (5) summary
      cd11261
      Location:195 → 654
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:655 → 706
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:713 → 718
      Ig; Ig strand A [structural motif]
      cl11960
      Location:713 → 792
      Ig; Immunoglobulin domain

    4. XM_038691613.1 → XP_038547541.1  semaphorin-4F isoform X1

      UniProtKB/TrEMBL
      A0A8C0NTE4, A0A8C0QBJ9, A0A8I3NZS3
      Related
      ENSCAFP00845023941.1, ENSCAFT00845030521.1
      Conserved Domains (5) summary
      cd11261
      Location:195 → 654
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:655 → 706
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:713 → 718
      Ig; Ig strand A [structural motif]
      cl11960
      Location:713 → 792
      Ig; Immunoglobulin domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049277.1 Alternate UMICH_Zoey_3.1

      Range
      48355887..48387283 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038499060.1 → XP_038354988.1  semaphorin-4F isoform X4

      Conserved Domains (4) summary
      cd11261
      Location:30 → 489
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:490 → 541
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00096
      Location:548 → 553
      Ig; Ig strand A [structural motif]
      cl11960
      Location:548 → 627
      Ig; Immunoglobulin domain

    2. XM_038499058.1 → XP_038354986.1  semaphorin-4F isoform X2

      Conserved Domains (5) summary
      smart00423
      Location:622 → 673
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:680 → 685
      Ig; Ig strand A [structural motif]
      cl11960
      Location:680 → 759
      Ig; Immunoglobulin domain
      cl15693
      Location:195 → 621
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    3. XM_038499059.1 → XP_038354987.1  semaphorin-4F isoform X3

      Conserved Domains (5) summary
      cd11261
      Location:195 → 654
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:655 → 706
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:713 → 718
      Ig; Ig strand A [structural motif]
      cl11960
      Location:713 → 792
      Ig; Immunoglobulin domain

    4. XM_038499057.1 → XP_038354985.1  semaphorin-4F isoform X1

      Conserved Domains (5) summary
      cd11261
      Location:195 → 654
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:655 → 706
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:713 → 718
      Ig; Ig strand A [structural motif]
      cl11960
      Location:713 → 792
      Ig; Immunoglobulin domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

      Range
      48420206..48451735 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038625689.1 → XP_038481617.1  semaphorin-4F isoform X4

      Conserved Domains (4) summary
      cd11261
      Location:30 → 489
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:490 → 541
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00096
      Location:548 → 553
      Ig; Ig strand A [structural motif]
      cl11960
      Location:548 → 627
      Ig; Immunoglobulin domain

    2. XM_038625687.1 → XP_038481615.1  semaphorin-4F isoform X2

      Conserved Domains (5) summary
      smart00423
      Location:622 → 673
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:680 → 685
      Ig; Ig strand A [structural motif]
      cl11960
      Location:680 → 759
      Ig; Immunoglobulin domain
      cl15693
      Location:195 → 621
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    3. XM_038625688.1 → XP_038481616.1  semaphorin-4F isoform X3

      Conserved Domains (5) summary
      cd11261
      Location:195 → 654
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:655 → 706
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:713 → 718
      Ig; Ig strand A [structural motif]
      cl11960
      Location:713 → 792
      Ig; Immunoglobulin domain

    4. XM_038625686.1 → XP_038481614.1  semaphorin-4F isoform X1

      Conserved Domains (5) summary
      cd11261
      Location:195 → 654
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:655 → 706
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:713 → 718
      Ig; Ig strand A [structural motif]
      cl11960
      Location:713 → 792
      Ig; Immunoglobulin domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

      Range
      48983164..49014582 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038561648.1 → XP_038417576.1  semaphorin-4F isoform X4

      UniProtKB/TrEMBL
      A0A8C0QBJ9, A0A8I3NZS3
      Conserved Domains (4) summary
      cd11261
      Location:30 → 489
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:490 → 541
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00096
      Location:548 → 553
      Ig; Ig strand A [structural motif]
      cl11960
      Location:548 → 627
      Ig; Immunoglobulin domain

    2. XM_038561646.1 → XP_038417574.1  semaphorin-4F isoform X2

      UniProtKB/TrEMBL
      A0A8C0QBD4, A0A8I3P073
      Conserved Domains (5) summary
      smart00423
      Location:622 → 673
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:680 → 685
      Ig; Ig strand A [structural motif]
      cl11960
      Location:680 → 759
      Ig; Immunoglobulin domain
      cl15693
      Location:195 → 621
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    3. XM_038561647.1 → XP_038417575.1  semaphorin-4F isoform X3

      UniProtKB/TrEMBL
      A0A8I3P4M6, A0A8P0T4R6
      Conserved Domains (5) summary
      cd11261
      Location:195 → 654
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:655 → 706
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:713 → 718
      Ig; Ig strand A [structural motif]
      cl11960
      Location:713 → 792
      Ig; Immunoglobulin domain

    4. XM_038561645.1 → XP_038417573.1  semaphorin-4F isoform X1

      UniProtKB/TrEMBL
      A0A8C0NTE4, A0A8C0QBJ9, A0A8I3NZS3
      Conserved Domains (5) summary
      cd11261
      Location:195 → 654
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:655 → 706
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:713 → 718
      Ig; Ig strand A [structural motif]
      cl11960
      Location:713 → 792
      Ig; Immunoglobulin domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      48121196..48152554 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022404780.2 → XP_022260488.1  semaphorin-4F isoform X4

      UniProtKB/TrEMBL
      A0A8C0QBJ9, A0A8I3NZS3
      Conserved Domains (4) summary
      cd11261
      Location:30 → 489
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:490 → 541
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00096
      Location:548 → 553
      Ig; Ig strand A [structural motif]
      cl11960
      Location:548 → 627
      Ig; Immunoglobulin domain

    2. XM_005630511.4 → XP_005630568.3  semaphorin-4F isoform X2

      UniProtKB/TrEMBL
      A0A8C0QBD4, A0A8I3P073
      Conserved Domains (5) summary
      smart00423
      Location:622 → 673
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:680 → 685
      Ig; Ig strand A [structural motif]
      cl11960
      Location:680 → 759
      Ig; Immunoglobulin domain
      cl15693
      Location:195 → 621
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    3. XM_022404779.2 → XP_022260487.2  semaphorin-4F isoform X3

      UniProtKB/TrEMBL
      A0A8I3P4M6, A0A8P0T4R6
      Conserved Domains (5) summary
      cd11261
      Location:195 → 654
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:655 → 706
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:713 → 718
      Ig; Ig strand A [structural motif]
      cl11960
      Location:713 → 792
      Ig; Immunoglobulin domain

    4. XM_540214.7 → XP_540214.5  semaphorin-4F isoform X1

      UniProtKB/TrEMBL
      A0A8C0QBJ9, A0A8I3NZS3
      Conserved Domains (5) summary
      cd11261
      Location:195 → 654
      Sema_4F; The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F)
      smart00423
      Location:655 → 706
      PSI; domain found in Plexins, Semaphorins and Integrins
      PHA03247
      Location:34 → 193
      PHA03247; large tegument protein UL36; Provisional
      cd00096
      Location:713 → 718
      Ig; Ig strand A [structural motif]
      cl11960
      Location:713 → 792
      Ig; Immunoglobulin domain
    Nucleotide Protein
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