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    LOXL3 lysyl oxidase like 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 483101, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LOXL3provided by VGNC
    Official Full Name
    lysyl oxidase like 3provided by VGNC
    Primary source
    VGNC:VGNC:42740
    See related
    Ensembl:ENSCAFG00845018096
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 17
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (49450304..49469724)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (48232758..48252169)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (49091871..49111294)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (48467472..48486874)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (48534207..48553616)

    Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene meiosis 1 associated protein Neighboring gene vesicle-associated membrane protein 3-like Neighboring gene S-phase kinase-associated protein 1-like Neighboring gene docking protein 1 Neighboring gene HtrA serine peptidase 2 Neighboring gene AUP1 lipid droplet regulating VLDL assembly factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-lysine 6-oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-lysine oxidation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lysyl oxidase homolog 3
    XP_005630578.1
    XP_022260490.1
    XP_038309030.1
    XP_038309031.1
    XP_038309032.1
    XP_038309033.1
    XP_038309034.1
    XP_038354989.1
    XP_038354990.1
    XP_038354991.1
    XP_038354992.1
    XP_038354993.1
    XP_038354994.1
    XP_038354995.1
    XP_038354996.1
    XP_038417577.1
    XP_038417578.1
    XP_038417579.1
    XP_038417580.1
    XP_038417581.1
    XP_038417582.1
    XP_038417583.1
    XP_038417584.1
    XP_038481618.1
    XP_038481619.1
    XP_038481620.1
    XP_038481621.1
    XP_038481622.1
    XP_038481623.1
    XP_038481624.1
    XP_038481625.1
    XP_038547545.1
    XP_038547546.1
    XP_038547547.1
    XP_038547548.1
    XP_038547549.1
    XP_038547550.1
    XP_038547551.1
    XP_038547552.1
    XP_852524.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051821.1 Reference ROS_Cfam_1.0

      Range
      49450304..49469724
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038691618.1 → XP_038547546.1  lysyl oxidase homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:358 → 458
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:581 → 780
      Lysyl_oxidase; Lysyl oxidase

    2. XM_038691617.1 → XP_038547545.1  lysyl oxidase homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:358 → 458
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:581 → 780
      Lysyl_oxidase; Lysyl oxidase

    3. XM_038691620.1 → XP_038547548.1  lysyl oxidase homolog 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:338 → 438
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:561 → 760
      Lysyl_oxidase; Lysyl oxidase

    4. XM_038691619.1 → XP_038547547.1  lysyl oxidase homolog 3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NPE0, A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:346 → 446
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:569 → 768
      Lysyl_oxidase; Lysyl oxidase

    5. XM_038691621.1 → XP_038547549.1  lysyl oxidase homolog 3 isoform X4

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:326 → 426
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:549 → 748
      Lysyl_oxidase; Lysyl oxidase

    6. XM_038691622.1 → XP_038547550.1  lysyl oxidase homolog 3 isoform X5

      UniProtKB/TrEMBL
      A0A8C0KLS2, A0A8C0NUH8, A0A8C0QD08, A0A8I3NVW6, A0A8I3S0C0
      Related
      ENSCAFP00845025212.1, ENSCAFT00845032254.1
      Conserved Domains (2) summary
      smart00202
      Location:307 → 407
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:530 → 729
      Lysyl_oxidase; Lysyl oxidase

    7. XM_038691623.1 → XP_038547551.1  lysyl oxidase homolog 3 isoform X6

      Conserved Domains (2) summary
      smart00202
      Location:52 → 160
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:165 → 364
      Lysyl_oxidase; Lysyl oxidase

    8. XM_038691624.1 → XP_038547552.1  lysyl oxidase homolog 3 isoform X7

      Conserved Domains (2) summary
      smart00202
      Location:56 → 164
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:169 → 368
      Lysyl_oxidase; Lysyl oxidase

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049277.1 Alternate UMICH_Zoey_3.1

      Range
      48467472..48486874
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038499062.1 → XP_038354990.1  lysyl oxidase homolog 3 isoform X1

      Conserved Domains (2) summary
      smart00202
      Location:358 → 458
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:581 → 780
      Lysyl_oxidase; Lysyl oxidase

    2. XM_038499061.1 → XP_038354989.1  lysyl oxidase homolog 3 isoform X1

      Conserved Domains (2) summary
      smart00202
      Location:358 → 458
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:581 → 780
      Lysyl_oxidase; Lysyl oxidase

    3. XM_038499064.1 → XP_038354992.1  lysyl oxidase homolog 3 isoform X3

      Conserved Domains (2) summary
      smart00202
      Location:338 → 438
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:561 → 760
      Lysyl_oxidase; Lysyl oxidase

    4. XM_038499063.1 → XP_038354991.1  lysyl oxidase homolog 3 isoform X2

      Conserved Domains (2) summary
      smart00202
      Location:346 → 446
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:569 → 768
      Lysyl_oxidase; Lysyl oxidase

    5. XM_038499065.1 → XP_038354993.1  lysyl oxidase homolog 3 isoform X4

      Conserved Domains (2) summary
      smart00202
      Location:326 → 426
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:549 → 748
      Lysyl_oxidase; Lysyl oxidase

    6. XM_038499066.1 → XP_038354994.1  lysyl oxidase homolog 3 isoform X5

      Conserved Domains (2) summary
      smart00202
      Location:307 → 407
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:530 → 729
      Lysyl_oxidase; Lysyl oxidase

    7. XM_038499067.1 → XP_038354995.1  lysyl oxidase homolog 3 isoform X6

      Conserved Domains (2) summary
      smart00202
      Location:52 → 160
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:165 → 364
      Lysyl_oxidase; Lysyl oxidase

    8. XM_038499068.1 → XP_038354996.1  lysyl oxidase homolog 3 isoform X7

      Conserved Domains (2) summary
      smart00202
      Location:56 → 164
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:169 → 368
      Lysyl_oxidase; Lysyl oxidase

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

      Range
      48534207..48553616
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038625691.1 → XP_038481619.1  lysyl oxidase homolog 3 isoform X1

      Conserved Domains (2) summary
      smart00202
      Location:358 → 458
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:581 → 780
      Lysyl_oxidase; Lysyl oxidase

    2. XM_038625690.1 → XP_038481618.1  lysyl oxidase homolog 3 isoform X1

      Conserved Domains (2) summary
      smart00202
      Location:358 → 458
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:581 → 780
      Lysyl_oxidase; Lysyl oxidase

    3. XM_038625693.1 → XP_038481621.1  lysyl oxidase homolog 3 isoform X3

      Conserved Domains (2) summary
      smart00202
      Location:338 → 438
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:561 → 760
      Lysyl_oxidase; Lysyl oxidase

    4. XM_038625692.1 → XP_038481620.1  lysyl oxidase homolog 3 isoform X2

      Conserved Domains (2) summary
      smart00202
      Location:346 → 446
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:569 → 768
      Lysyl_oxidase; Lysyl oxidase

    5. XM_038625694.1 → XP_038481622.1  lysyl oxidase homolog 3 isoform X4

      Conserved Domains (2) summary
      smart00202
      Location:326 → 426
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:549 → 748
      Lysyl_oxidase; Lysyl oxidase

    6. XM_038625695.1 → XP_038481623.1  lysyl oxidase homolog 3 isoform X5

      Conserved Domains (2) summary
      smart00202
      Location:307 → 407
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:530 → 729
      Lysyl_oxidase; Lysyl oxidase

    7. XM_038625696.1 → XP_038481624.1  lysyl oxidase homolog 3 isoform X6

      Conserved Domains (2) summary
      smart00202
      Location:52 → 160
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:165 → 364
      Lysyl_oxidase; Lysyl oxidase

    8. XM_038625697.1 → XP_038481625.1  lysyl oxidase homolog 3 isoform X7

      Conserved Domains (2) summary
      smart00202
      Location:56 → 164
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:169 → 368
      Lysyl_oxidase; Lysyl oxidase

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

      Range
      49091871..49111294
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038561650.1 → XP_038417578.1  lysyl oxidase homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:358 → 458
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:581 → 780
      Lysyl_oxidase; Lysyl oxidase

    2. XM_038561649.1 → XP_038417577.1  lysyl oxidase homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:358 → 458
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:581 → 780
      Lysyl_oxidase; Lysyl oxidase

    3. XM_038561652.1 → XP_038417580.1  lysyl oxidase homolog 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:338 → 438
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:561 → 760
      Lysyl_oxidase; Lysyl oxidase

    4. XM_038561651.1 → XP_038417579.1  lysyl oxidase homolog 3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NPE0, A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:346 → 446
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:569 → 768
      Lysyl_oxidase; Lysyl oxidase

    5. XM_038561653.1 → XP_038417581.1  lysyl oxidase homolog 3 isoform X4

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:326 → 426
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:549 → 748
      Lysyl_oxidase; Lysyl oxidase

    6. XM_038561654.1 → XP_038417582.1  lysyl oxidase homolog 3 isoform X5

      UniProtKB/TrEMBL
      A0A8C0KLS2, A0A8C0NUH8, A0A8C0QD08, A0A8I3NVW6, A0A8I3S0C0
      Conserved Domains (2) summary
      smart00202
      Location:307 → 407
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:530 → 729
      Lysyl_oxidase; Lysyl oxidase

    7. XM_038561655.1 → XP_038417583.1  lysyl oxidase homolog 3 isoform X6

      Conserved Domains (2) summary
      smart00202
      Location:52 → 160
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:165 → 364
      Lysyl_oxidase; Lysyl oxidase

    8. XM_038561656.1 → XP_038417584.1  lysyl oxidase homolog 3 isoform X7

      Conserved Domains (2) summary
      smart00202
      Location:56 → 164
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:169 → 368
      Lysyl_oxidase; Lysyl oxidase

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      48232758..48252169
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038453103.1 → XP_038309031.1  lysyl oxidase homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:358 → 458
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:581 → 780
      Lysyl_oxidase; Lysyl oxidase

    2. XM_038453102.1 → XP_038309030.1  lysyl oxidase homolog 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:358 → 458
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:581 → 780
      Lysyl_oxidase; Lysyl oxidase

    3. XM_038453104.1 → XP_038309032.1  lysyl oxidase homolog 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:338 → 438
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:561 → 760
      Lysyl_oxidase; Lysyl oxidase

    4. XM_005630521.4 → XP_005630578.1  lysyl oxidase homolog 3 isoform X2

      See identical proteins and their annotated locations for XP_005630578.1

      UniProtKB/TrEMBL
      A0A8C0NPE0, A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:346 → 446
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:569 → 768
      Lysyl_oxidase; Lysyl oxidase

    5. XM_038453105.1 → XP_038309033.1  lysyl oxidase homolog 3 isoform X4

      UniProtKB/TrEMBL
      A0A8C0QD08, A0A8I3NVW6
      Conserved Domains (2) summary
      smart00202
      Location:326 → 426
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:549 → 748
      Lysyl_oxidase; Lysyl oxidase

    6. XM_847431.6 → XP_852524.1  lysyl oxidase homolog 3 isoform X5

      UniProtKB/TrEMBL
      A0A8C0KLS2, A0A8C0NUH8, A0A8C0QD08, A0A8I3NVW6, A0A8I3S0C0
      Conserved Domains (2) summary
      smart00202
      Location:307 → 407
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:530 → 729
      Lysyl_oxidase; Lysyl oxidase

    7. XM_022404782.2 → XP_022260490.1  lysyl oxidase homolog 3 isoform X6

      Conserved Domains (2) summary
      smart00202
      Location:52 → 160
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:165 → 364
      Lysyl_oxidase; Lysyl oxidase

    8. XM_038453106.1 → XP_038309034.1  lysyl oxidase homolog 3 isoform X7

      Conserved Domains (2) summary
      smart00202
      Location:56 → 164
      SR; Scavenger receptor Cys-rich
      pfam01186
      Location:169 → 368
      Lysyl_oxidase; Lysyl oxidase
    Nucleotide Protein
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