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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852342, updated on 28-Oct-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000000257
    Locus tag
    YBR053C
    See related
    AllianceGenome:SGD:S000000257; FungiDB:YBR053C; VEuPathDB:YBR053C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable calcium ion binding activity and gluconolactonase activity. Predicted to be involved in L-ascorbic acid biosynthetic process. Orthologous to human RGN (regucalcin). [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

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    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (339675..340751, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene protein phosphatase regulator REG2 Neighboring gene flavodoxin-like fold family protein Neighboring gene Yro2p Neighboring gene U4/U6-U5 snRNP complex subunit PRP6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the transcriptional response to cell wall stress in Saccharomyces cerevisiae. Boorsma A, et al. Yeast, 2004 Apr 15. PMID 15116342
    2. Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated. Voynova NS, et al. Eukaryot Cell, 2015 Dec. PMID 26432633, Free PMC Article
    3. Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins. Tonikian R, et al. PLoS Biol, 2009 Oct. PMID 19841731, Free PMC Article
    4. Complete DNA sequence of yeast chromosome II. Feldmann H, et al. EMBO J, 1994 Dec 15. PMID 7813418, Free PMC Article
    5. The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range. Girstmair H, et al. Nat Commun, 2019 Aug 9. PMID 31399574, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gluconolactonase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-ascorbic acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_009609.1
    • hypothetical protein; induced by cell wall perturbation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      339675..340751 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178401.1 → NP_009609.1  TPA: uncharacterized protein YBR053C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009609.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQ52, P38235, Q6Q5P3
      UniProtKB/TrEMBL
      A6ZKZ6, B3LN96, B5VE18, D3UEE8, G2W958, N1P6H3
      Conserved Domains (2) summary
      COG3386
      Location:1 → 345
      YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
      sd00039
      Location:150 → 186
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38235.1

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