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    DTR1 Dtr1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852478, updated on 18-Sep-2024

    Summary

    Official Symbol
    DTR1
    Official Full Name
    Dtr1p
    Primary source
    SGD:S000000384
    Locus tag
    YBR180W
    See related
    AllianceGenome:SGD:S000000384; FungiDB:YBR180W; VEuPathDB:YBR180W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables amine transmembrane transporter activity. Involved in amine transport; ascospore wall assembly; and transmembrane transport. Located in prospore membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See DTR1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (589741..591459)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene medium-chain fatty acid ethyl ester synthase/esterase Neighboring gene mitofusin Neighboring gene ribosomal 40S subunit protein S6B Neighboring gene Smp1p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables amine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables amine transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in amine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in amine transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in ascospore wall assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in prospore membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in prospore membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Dtr1p
    NP_009739.1
    • Putative dityrosine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; required for spore wall synthesis; sequence similarity to QDR1 and QDR3, and the triple mutant dtr1 qdr1 qdr3 exhibits reduced dityrosine fluorescence relative to the single mutants; expressed during sporulation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      589741..591459
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178528.1NP_009739.1  TPA: Dtr1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009739.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQH4, P38125
      UniProtKB/TrEMBL
      G2W9I1, N1PAU5
      Conserved Domains (1) summary
      cd17323
      Location:124567
      MFS_Tpo1_MDR_like; Yeast Polyamine transporter 1 (Tpo1) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily