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    ERT1 Ert1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852541, updated on 18-Sep-2024

    Summary

    Official Symbol
    ERT1
    Official Full Name
    Ert1p
    Primary source
    SGD:S000000443
    Locus tag
    YBR239C
    See related
    AllianceGenome:SGD:S000000443; FungiDB:YBR239C; VEuPathDB:YBR239C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source and positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See ERT1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (698354..699943, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene DEAD-box RNA helicase PRP5 Neighboring gene uncharacterized protein Neighboring gene Thi2p Neighboring gene Vvs1p

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Ert1p
    NP_009798.3
    • Transcriptional regulator; involved in regulation of gluconeogenesis and fermentable carbon utilization; GFP-fusion protein localizes to cytoplasm, nucleus; null mutation affects periodicity of transcriptional and metabolic oscillation; plays role in restricting Ty1 transposition; member of the zinc cluster family of proteins, similar to Rds2p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      698354..699943 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178587.3NP_009798.3  TPA: Ert1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009798.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZLH8, D6VQN5, P38140
      UniProtKB/TrEMBL
      G2W9P2
      Conserved Domains (2) summary
      cd00067
      Location:3669
      GAL4; GAL4-like Zn2Cys6 binuclear cluster DNA-binding domain; found in transcription regulators like GAL4. Domain consists of two helices organized around a Zn(2)Cys(6 )motif; Binds to sequences containing 2 DNA half sites comprised of 3-5 C/G combinations
      pfam00989
      Location:411527
      PAS; PAS fold