U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FYV5 Fyv5p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850299, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FYV5
    Official Full Name
    Fyv5p
    Primary source
    SGD:S000000563
    Locus tag
    YCL058C
    See related
    AllianceGenome:SGD:S000000563; FungiDB:YCL058C; VEuPathDB:YCL058C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MDF1
    Summary
    Involved in cellular ion homeostasis; negative regulation of transcription by RNA polymerase II; and pheromone-dependent signal transduction involved in conjugation with cellular fusion. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FYV5 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_001135.5 (23523..23981, complement)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene chromatin-modulating protein MRC1 Neighboring gene ribosome biosynthesis protein KRR1 Neighboring gene Adf1p Neighboring gene Mic10p Neighboring gene metalloendopeptidase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001135.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. How to bring orphan genes into functional families. Bianchi MM, et al. Yeast, 1999 Apr. PMID 10234789
    2. Pleiotropy of the de novo-originated gene MDF1. Li D, et al. Sci Rep, 2014 Dec 2. PMID 25452167, Free PMC Article
    3. A de novo originated gene depresses budding yeast mating pathway and is repressed by the protein encoded by its antisense strand. Li D, et al. Cell Res, 2010 Apr. PMID 20195295
    4. Systematic genetic modifications of cell wall biosynthesis enhanced the secretion and surface-display of polysaccharide degrading enzymes in Saccharomyces cerevisiae. Chen N, et al. Metab Eng, 2023 May. PMID 37100192
    5. A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer toxin. Pagé N, et al. Genetics, 2003 Mar. PMID 12663529, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular monoatomic ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pheromone-dependent signal transduction involved in conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Fyv5p
    NP_009873.1
    • De novo-originated gene from non-coding sequence; protein can suppress mating and promote vegetative growth; shortens lag phase by physically interacting with Snf1p; binds with Matalpha2p to promoters of haploid-specific genes; functions in mating and fermentation, mediates crosstalk between reproduction and vegetative growth; required for survival upon exposure to K1 killer toxin; involved in ion homeostasis

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      23523..23981 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178702.1 → NP_009873.1  TPA: Fyv5p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009873.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQU8, P25585
      UniProtKB/TrEMBL
      B5VEQ3, C8Z431
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25585.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools