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    RPS24A ribosomal 40S subunit protein S24A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856805, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPS24A
    Official Full Name
    ribosomal 40S subunit protein S24A
    Primary source
    SGD:S000000876
    Locus tag
    YER074W
    See related
    AllianceGenome:SGD:S000000876; FungiDB:YER074W; VEuPathDB:YER074W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPS24EA
    Summary
    Predicted to be a structural constituent of ribosome. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in mitochondrion. Human ortholog(s) of this gene implicated in Diamond-blackfan anemia 3. Orthologous to human RPS24 (ribosomal protein S24). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPS24A in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    2
    Sequence:
    Chromosome: V; NC_001137.3 (306323..307196)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Vtc1p Neighboring gene aldehyde dehydrogenase (NAD(P)(+)) ALD5 Neighboring gene Yos1p Neighboring gene tyrosine protein phosphatase PTP3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. 5´-UTR introns enhance protein expression in the yeast Saccharomyces cerevisiae. Hoshida H, et al. Appl Microbiol Biotechnol, 2017 Jan. PMID 27734122
    2. Ribosomal proteins produced in excess are degraded by the ubiquitin-proteasome system. Sung MK, et al. Mol Biol Cell, 2016 Sep 1. PMID 27385339, Free PMC Article
    3. Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Roberts TM, et al. Mol Biol Cell, 2006 Jan. PMID 16267268, Free PMC Article
    4. Dosage rescue by UBC4 restores cell wall integrity in Saccharomyces cerevisiae lacking the myosin type II gene MYO1. Díaz-Blanco NL, et al. Yeast, 2007 Apr. PMID 17397110, Free PMC Article
    5. Deciphering protein complexes and protein interaction networks by tandem affinity purification and mass spectrometry: analytical perspective. Shevchenko A, et al. Mol Cell Proteomics, 2002 Mar. PMID 12096120

    See all (89) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S24A
    NP_010997.3
    • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S24, no bacterial homolog; RPS24A has a paralog, RPS24B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      306323..307196
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178965.3 → NP_010997.3  TPA: ribosomal 40S subunit protein S24A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010997.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLX9, P0CX31, P0CX32, P26782
      UniProtKB/TrEMBL
      A6ZR28, C8Z782, G2WG79, N1P3F2
      Conserved Domains (1) summary
      PTZ00071
      Location:1 → 123
      PTZ00071; 40S ribosomal protein S24; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CX31.1
    P0CX32.1

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