FLO8 pseudo [Saccharomyces cerevisiae S288C] - Gene

Summary

Gene symbol: FLO8
Gene description: pseudo
Locus tag: YER109C
See related: FungiDB:YER109C; VEuPathDB:YER109C
Gene type: pseudo
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: PHD5; STA10; YER108C
NEW: Try the new Gene table
Try the new Transcript table

Chromosome V - NC_001137.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Flo8 and Mss11 can directly form either a heterodimer or a homodimer capable of binding to DNA, and this formed complex of two activators interacts functionally and physically with the Swi/Snf complex.
Title: Two distinct domains of Flo8 activator mediates its role in transcriptional activation and the physical interaction with Mss11.
Mss11p, together with Flo8p, induces flocculation in Saccharomyces cerevisiae
Title: The regulation of Saccharomyces cerevisiae FLO gene expression and Ca2+ -dependent flocculation by Flo8p and Mss11p.
The amber mutation of the transcriptional activator, FLO8, represses glucoamylase gene expression.
Title: STA10 repression of STA gene expression is caused by a defective activator, flo8, in Saccharomyces cerevisiae.
Flo8 interacts physically and functionally with Mss11
Title: Recruitment of the Swi/Snf complex by Ste12-Tec1 promotes Flo8-Mss11-mediated activation of STA1 expression.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Transcription factor; required for flocculation, diploid filamentous growth, and haploid invasive growth; forms a heterodimer with Mss11p that interacts with the Swi/Snf complex during transcriptional activation of FLO1, FLO11, and STA1; S. cerevisiae genome reference strain S288C contains an internal in-frame stop at codon 142, which in other strains encodes tryptophan

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of cell adhesion involved in single-species biofilm formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of flocculation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of invasive growth in response to glucose limitation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of pseudohyphal growth	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of pseudohyphal growth	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of starch catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of primary metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
located_in nucleus	HDA more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info