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    IMO32 Imo32p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852919, updated on 17-May-2024

    Summary

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    Gene symbol
    IMO32
    Gene description
    Imo32p
    Primary source
    FungiDB:YGR031W
    Locus tag
    YGR031W
    See related
    SGD:S000003263; AllianceGenome:SGD:S000003263; VEuPathDB:YGR031W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables triglyceride lipase activity. Involved in cellular lipid metabolic process. Located in mitochondrion. Orthologous to human ABHD11 (abhydrolase domain containing 11). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See IMO32 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (546441..547469)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ribonuclease P/MRP protein subunit POP6 Neighboring gene Nag1p Neighboring gene 1,3-beta-glucan synthase GSC2 Neighboring gene Tim21p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Human alpha beta hydrolase domain containing protein 11 and its yeast homolog are lipid hydrolases. Arya M, et al. Biochem Biophys Res Commun, 2017 Jun 10. PMID 28465236
    2. Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization. Vögtle FN, et al. Mol Biol Cell, 2011 Jul 1. PMID 21525245, Free PMC Article
    3. A Whi7-anchored loop controls the G1 Cdk-cyclin complex at start. Yahya G, et al. Mol Cell, 2014 Jan 9. PMID 24374311
    4. Analysis of the TORC1 interactome reveals a spatially distinct function of TORC1 in mRNP complexes. Chang Y, et al. J Cell Biol, 2021 Apr 5. PMID 33566094, Free PMC Article
    5. Mitochondrial heat shock protein (Hsp) 70 and Hsp10 cooperate in the formation of Hsp60 complexes. Böttinger L, et al. J Biol Chem, 2015 May 1. PMID 25792736, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables carboxylic ester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables triglyceride lipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables triglyceride lipase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular lipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellular lipid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in cellular lipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Imo32p
    NP_011545.1
    • Conserved mitochondrial hypothetical protein; processed by both mitochondrial processing peptidase and mitochondrial octapeptidyl aminopeptidase; gene contains the nested antisense gene NAG1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      546441..547469
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181160.1 → NP_011545.1  TPA: Imo32p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011545.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUG6, P53219, Q45U54
      UniProtKB/TrEMBL
      A6ZV19, B3LII9, B5VIZ0, C7GK98, C8Z8S5, N1P3T6
      Conserved Domains (1) summary
      PRK10673
      Location:74 → 326
      PRK10673; esterase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53219.1

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