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    IKS1 protein kinase IKS1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853389, updated on 18-Sep-2024

    Summary

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    Official Symbol
    IKS1
    Official Full Name
    protein kinase IKS1
    Primary source
    SGD:S000003593
    Locus tag
    YJL057C
    See related
    AllianceGenome:SGD:S000003593; FungiDB:YJL057C; VEuPathDB:YJL057C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables protein kinase activity. Involved in protein phosphorylation. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See IKS1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (328118..330121, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene amino acid transporter YHC3 Neighboring gene Bit61p Neighboring gene Zap1p Neighboring gene Log1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene-Environment Interactions in Stress Response Contribute Additively to a Genotype-Environment Interaction. Matsui T, et al. PLoS Genet, 2016 Jul. PMID 27437938, Free PMC Article
    2. Improvement of acetic acid tolerance of Saccharomyces cerevisiae using a zinc-finger-based artificial transcription factor and identification of novel genes involved in acetic acid tolerance. Ma C, et al. Appl Microbiol Biotechnol, 2015 Mar. PMID 25698512
    3. Screening the yeast deletant mutant collection for hypersensitivity and hyper-resistance to sorbate, a weak organic acid food preservative. Mollapour M, et al. Yeast, 2004 Aug. PMID 15334557
    4. Chemotyping of yeast mutants using robotics. Rieger KJ, et al. Yeast, 1999 Jul. PMID 10407277
    5. Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae. Sakaki K, et al. J Biochem, 2003 Sep. PMID 14561723

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity HDA PubMed 
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein phosphorylation HDA PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein kinase IKS1
    NP_012478.3
    • Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      328118..330121 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181490.3 → NP_012478.3  TPA: protein kinase IKS1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012478.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWC5, P47042
      UniProtKB/TrEMBL
      A6ZPR6, N1NZV7
      Conserved Domains (1) summary
      cl21453
      Location:173 → 522
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47042.1

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