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    CBP1 Cbp1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853221, updated on 17-May-2024

    Summary

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    Gene symbol
    CBP1
    Gene description
    Cbp1p
    Primary source
    FungiDB:YJL209W
    Locus tag
    YJL209W
    See related
    SGD:S000003745; AllianceGenome:SGD:S000003745; VEuPathDB:YJL209W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables mRNA binding activity. Involved in aerobic respiration and mitochondrial mRNA catabolic process. Located in mitochondrion. Is extrinsic component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See CBP1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (38005..39969)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene oligopeptide transporter OPT1 Neighboring gene ubiquitin-protein ligase peroxin 2 Neighboring gene ribonuclease Neighboring gene Laa1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Premature 3'-end formation of CBP1 mRNA results in the downregulation of cytochrome b mRNA during the induction of respiration in Saccharomyces cerevisiae. Sparks KA, et al. Mol Cell Biol, 1997 Aug. PMID 9234677, Free PMC Article
    2. Generation of temperature-sensitive cbp1 strains of Saccharomyces cerevisiae by PCR mutagenesis and in vivo recombination: characteristics of the mutant strains imply that CBP1 is involved in stabilization and processing of cytochrome b pre-mRNA. Staples RR, et al. Genetics, 1993 Dec. PMID 8307338, Free PMC Article
    3. Identification and cloning of a yeast nuclear gene (CBP1) involved in expression of mitochondrial cytochrome b. Dieckmann CL, et al. Proc Natl Acad Sci U S A, 1982 Mar. PMID 7043464, Free PMC Article
    4. Assembly of the mitochondrial membrane system. Nucleotide sequence of a yeast nuclear gene (CBP1) involved in 5' end processing of cytochrome b pre-mRNA. Dieckmann CL, et al. J Biol Chem, 1984 Apr 25. PMID 6325407
    5. The yeast CBP1 gene produces two differentially regulated transcripts by alternative 3'-end formation. Mayer SA, et al. Mol Cell Biol, 1989 Oct. PMID 2573826, Free PMC Article

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mitochondrial localization of the splicing endonuclease complex is required for the cleavage of the CBP1 mRNA.
      Title: The tRNA Splicing Endonuclease Complex Cleaves the Mitochondria-localized CBP1 mRNA.
    2. Data suggests that Cbp1 is loosely associated with the mitochondrial membrane through weak hydrophobic interactions and it is part of a single 900,000-Da complex. .
      Title: The mitochondrial message-specific mRNA protectors Cbp1 and Pet309 are associated in a high-molecular weight complex.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in aerobic respiration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial mRNA catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Cbp1p
    NP_012326.1
    • Mitochondrial protein, regulator of COB mRNA stability and translation; interacts with the 5'-untranslated region of the COB mRNA; found in a complex at the inner membrane along with Pet309p; localizes to mitochondrial foci upon DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      38005..39969
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181642.1 → NP_012326.1  TPA: Cbp1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012326.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVY5, P07252
      UniProtKB/TrEMBL
      A0A8H4BZD7, N1P174
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P07252.1

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