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    ARP6 Arp6p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850774, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ARP6
    Official Full Name
    Arp6p
    Primary source
    SGD:S000004075
    Locus tag
    YLR085C
    See related
    AllianceGenome:SGD:S000004075; FungiDB:YLR085C; VEuPathDB:YLR085C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables nucleosome binding activity. Involved in histone exchange. Located in cytoplasm and nuclear periphery. Part of Swr1 complex. Orthologous to human ACTR6 (actin related protein 6). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See ARP6 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (300673..301989, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Emp70p Neighboring gene Rax2p Neighboring gene condensin subunit SMC4 Neighboring gene Csf1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast Actin-Related Protein ARP6 Negatively Regulates Agrobacterium-Mediated Transformation of Yeast Cell. Luo Y, et al. Biomed Res Int, 2015. PMID 26425545, Free PMC Article
    2. Actin-related protein Arp6 influences H2A.Z-dependent and -independent gene expression and links ribosomal protein genes to nuclear pores. Yoshida T, et al. PLoS Genet, 2010 Apr 15. PMID 20419146, Free PMC Article
    3. The INO80 complex is required for damage-induced recombination. Kawashima S, et al. Biochem Biophys Res Commun, 2007 Apr 13. PMID 17320816
    4. The nuclear actin-related protein ARP6 is a pleiotropic developmental regulator required for the maintenance of FLOWERING LOCUS C expression and repression of flowering in Arabidopsis. Deal RB, et al. Plant Cell, 2005 Oct. PMID 16141450, Free PMC Article
    5. Multiple actin-related proteins of Saccharomyces cerevisiae are present in the nucleus. Harata M, et al. J Biochem, 2000 Oct. PMID 11011149

    See all (98) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables nucleosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleosome binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin remodeling IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Swr1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Swr1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in intracellular non-membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Arp6p
    NP_013186.1
    • Actin-related protein that binds nucleosomes; a component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      300673..301989 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181972.1 → NP_013186.1  TPA: Arp6p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013186.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY85, Q12509
      UniProtKB/TrEMBL
      A7A0Y9, B3LT53, C7GQQ9, C8ZD56, G2WIS7, N1NZJ6
      Conserved Domains (1) summary
      smart00268
      Location:3 → 433
      ACTIN; Actin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12509.1

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