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    BLS1 Bls1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851124, updated on 2-Nov-2024

    Summary

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    Official Symbol
    BLS1
    Official Full Name
    Bls1p
    Primary source
    SGD:S000004400
    Locus tag
    YLR408C
    See related
    AllianceGenome:SGD:S000004400; FungiDB:YLR408C; VEuPathDB:YLR408C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in endosome organization and regulation of protein localization. Located in endosome. Part of BLOC-1 complex. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See BLS1 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (933885..934253, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Gag1p Neighboring gene rRNA-processing protein UTP21 Neighboring gene inositol polyphosphate kinase VIP1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast homologues of three BLOC-1 subunits highlight KxDL proteins as conserved interactors of BLOC-1. Hayes MJ, et al. Traffic, 2011 Mar. PMID 21159114, Free PMC Article
    2. The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3. John Peter AT, et al. J Cell Biol, 2013 Apr 1. PMID 23547030, Free PMC Article
    3. Identification of a Rab GTPase-activating protein cascade that controls recycling of the Rab5 GTPase Vps21 from the vacuole. Rana M, et al. Mol Biol Cell, 2015 Jul 1. PMID 25971802, Free PMC Article
    4. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549
    5. A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking. Aguilar PS, et al. Nat Struct Mol Biol, 2010 Jul. PMID 20526336, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in endosome organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of BLOC-1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of BLOC-1 complex ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    located_in endosome HDA PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Bls1p
    NP_013512.1
    • Subunit of the BLOC-1 complex involved in endosomal maturation; green fluorescent protein (GFP)-fusion protein localizes to the endosome; YLR408C is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      933885..934253 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182296.1 → NP_013512.1  TPA: Bls1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013512.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A7A1T1, B3RHR9, C8ZE17, D6VZ42, E7LY32, E7NL30, E7Q7C0, E7QIC5, Q06071
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06071.1

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