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    YIP3 Yip3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855683, updated on 28-Oct-2024

    Summary

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    Official Symbol
    YIP3
    Official Full Name
    Yip3p
    Primary source
    SGD:S000004989
    Locus tag
    YNL044W
    See related
    AllianceGenome:SGD:S000004989; FungiDB:YNL044W; VEuPathDB:YNL044W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and peroxisome. Orthologous to human RABAC1 (Rab acceptor 1). [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

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    See YIP3 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    2
    Sequence:
    Chromosome: XIV; NC_001146.8 (545268..545877)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene bifunctional aminopeptidase/epoxide hydrolase Neighboring gene tRNA-Pro Neighboring gene uncharacterized protein Neighboring gene Bop3p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Saccharomyces cerevisiae Rab-GDI displacement factor ortholog Yip3p forms distinct complexes with the Ypt1 Rab GTPase and the reticulon Rtn1p. Geng J, et al. Eukaryot Cell, 2005 Jul. PMID 16002643, Free PMC Article
    2. Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins. Calero M, et al. Biochem Biophys Res Commun, 2002 Jan 18. PMID 11785952
    3. Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. Otte S, et al. J Cell Biol, 2001 Feb 5. PMID 11157978, Free PMC Article
    4. Translation- and SRP-independent mRNA targeting to the endoplasmic reticulum in the yeast Saccharomyces cerevisiae. Kraut-Cohen J, et al. Mol Biol Cell, 2013 Oct. PMID 23904265, Free PMC Article
    5. Pls1 Is a Peroxisomal Matrix Protein with a Role in Regulating Lysine Biosynthesis. David Y, et al. Cells, 2022 Apr 22. PMID 35563734, Free PMC Article

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Yip3 protein may have multiple functions and that its interaction with Rabs is not critical for their recruitment to organelle membranes.
      Title: Saccharomyces cerevisiae Rab-GDI displacement factor ortholog Yip3p forms distinct complexes with the Ypt1 Rab GTPase and the reticulon Rtn1p.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in COPII-coated ER to Golgi transport vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Yip3p
    NP_014354.2
    • Protein localized to COPII vesicles; proposed to be involved in ER-to-Golgi transport; interacts with members of the Rab GTPase family and Yip1p; also interacts with Rtn1p; integral membrane protein that localizes to the ER, the Golgi apparatus, transport vesicles and the peroxisome; two isoforms exist, a full-length Yip3L (Yip3 Long) and a shorter peroxisomal matrix isoform Yip3S (Yip3 Short)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      545268..545877
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182883.1 → NP_014354.2  TPA: Yip3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014354.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1D5, P53633
      UniProtKB/TrEMBL
      A6ZS34, B3LNQ6, C7GLV6, C8ZGI4, G2WM59, N1NXL4
      Conserved Domains (1) summary
      COG5130
      Location:1 → 176
      YIP3; Prenylated rab acceptor 1 and related proteins [Intracellular trafficking and secretion / Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53633.2

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