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    CIM1 mitochondrial HMG-box protein CIM1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854281, updated on 2-Nov-2024

    Summary

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    Official Symbol
    CIM1
    Official Full Name
    mitochondrial HMG-box protein CIM1
    Primary source
    SGD:S000005640
    Locus tag
    YOR114W
    See related
    AllianceGenome:SGD:S000005640; FungiDB:YOR114W; VEuPathDB:YOR114W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    DPI34
    Summary
    Acts upstream of or within mitochondrial genome maintenance. Is active in mitochondrial matrix. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See CIM1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (537570..538454)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Cex1p Neighboring gene Azf1p Neighboring gene Trs33p Neighboring gene DNA-directed RNA polymerase III core subunit RPO31

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two mitochondrial HMG-box proteins, Cim1 and Abf2, antagonistically regulate mtDNA copy number in Saccharomyces cerevisiae. Schrott S, et al. Nucleic Acids Res, 2023 Nov 27. PMID 37850632, Free PMC Article
    2. Polymorphisms in multiple genes contribute to the spontaneous mitochondrial genome instability of Saccharomyces cerevisiae S288C strains. Dimitrov LN, et al. Genetics, 2009 Sep. PMID 19581448, Free PMC Article
    3. Two Routes to Genetic Suppression of RNA Trimethylguanosine Cap Deficiency via C-Terminal Truncation of U1 snRNP Subunit Snp1 or Overexpression of RNA Polymerase Subunit Rpo26. Qiu ZR, et al. G3 (Bethesda), 2015 Apr 24. PMID 25911228, Free PMC Article
    4. Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale. Morgenstern M, et al. Cell Rep, 2017 Jun 27. PMID 28658629, Free PMC Article
    5. Yeast Nst1 is a novel component of P-bodies and is a specific suppressor of proteasome base assembly defects. Cheng CL, et al. Mol Biol Cell, 2021 Oct 1. PMID 34347506, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Two mitochondrial HMG-box proteins, Cim1 and Abf2, antagonistically regulate mtDNA copy number in Saccharomyces cerevisiae.
      Title: Two mitochondrial HMG-box proteins, Cim1 and Abf2, antagonistically regulate mtDNA copy number in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mitochondrial genome maintenance IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within mitochondrial genome maintenance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial HMG-box protein CIM1
    NP_014757.1
    • Mitochondrial HMG-box protein; limits the copy number of mitochondrial DNA (mtDNA), antagonizing HMG-box containing protein Abf2p, a mtDNA packaging factor; localizes to the mitochondrial matrix; contains two HMG-boxes similar to Abf2p; null mutant is viable

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      537570..538454
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183533.1 → NP_014757.1  TPA: mitochondrial HMG-box protein CIM1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014757.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2H3, Q12219
      UniProtKB/TrEMBL
      A6ZNW2, C7GMM2, G2WMZ0, N1P345
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12219.1

    Gene LinkOut

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