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    GEP3 Gep3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854380, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GEP3
    Official Full Name
    Gep3p
    Primary source
    SGD:S000005731
    Locus tag
    YOR205C
    See related
    AllianceGenome:SGD:S000005731; FungiDB:YOR205C; VEuPathDB:YOR205C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    AIM40; FMP38; MTG3
    Summary
    Predicted to enable GTP binding activity. Involved in maturation of SSU-rRNA. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See GEP3 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (725564..727234, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene imidazoleglycerol-phosphate dehydratase HIS3 Neighboring gene DEAD-box ATP-dependent RNA helicase DED1 Neighboring gene mRNA-binding ribosome synthesis protein NOC2 Neighboring gene DNA-directed RNA polymerase III core subunit RET1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The putative GTPase encoded by MTG3 functions in a novel pathway for regulating assembly of the small subunit of yeast mitochondrial ribosomes. Paul MF, et al. J Biol Chem, 2012 Jul 13. PMID 22621929, Free PMC Article
    2. Mitochondrial ribosomal proteins involved in tellurite resistance in yeast Saccharomyces cerevisiae. Pontieri P, et al. Sci Rep, 2018 Aug 13. PMID 30104660, Free PMC Article
    3. Assessing systems properties of yeast mitochondria through an interaction map of the organelle. Perocchi F, et al. PLoS Genet, 2006 Oct 20. PMID 17054397, Free PMC Article
    4. The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. Osman C, et al. J Cell Biol, 2009 Feb 23. PMID 19221197, Free PMC Article
    5. Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex. Vukotic M, et al. Cell Metab, 2012 Mar 7. PMID 22342701

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Gep3p
    NP_014848.1
    • Protein required for mitochondrial ribosome small subunit biogenesis; null mutant is defective in respiration and in maturation of 15S rRNA; protein is localized to the mitochondrial inner membrane; null mutant interacts synthetically with prohibitin (Phb1p)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      725564..727234 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183624.1 → NP_014848.1  TPA: Gep3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014848.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZP48, D6W2R1, Q08622
      UniProtKB/TrEMBL
      N1NVV1
      Conserved Domains (1) summary
      cd01855
      Location:94 → 302
      YqeH; Circularly permuted YqeH GTPase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08622.1

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