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    SSP2 Ssp2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854416, updated on 2-Nov-2024

    Summary

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    Official Symbol
    SSP2
    Official Full Name
    Ssp2p
    Primary source
    SGD:S000005768
    Locus tag
    YOR242C
    See related
    AllianceGenome:SGD:S000005768; FungiDB:YOR242C; VEuPathDB:YOR242C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables protein kinase activator activity. Involved in ascospore wall assembly and positive regulation of protein autophosphorylation. Located in ascospore wall. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See SSP2 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (788742..789857, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene tRNA(Thr) (cytosine(32)-N(3))-methyltransferase Neighboring gene tetrahydrofolate synthase Neighboring gene pseudouridine synthase PUS7 Neighboring gene NuA4 histone acetyltransferase complex catalytic subunit ESA1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SSP2, a sporulation-specific gene necessary for outer spore wall assembly in the yeast Saccharomyces cerevisiae. Sarkar PK, et al. Mol Genet Genomics, 2002 May. PMID 12073037
    2. RNA Recognition-like Motifs Activate a Mitogen-Activated Protein Kinase. Phillips T, et al. Biochemistry, 2018 Dec 18. PMID 30452242, Free PMC Article
    3. Ssp2 Binding Activates the Smk1 Mitogen-Activated Protein Kinase. Tio CW, et al. Mol Cell Biol, 2017 May 15. PMID 28223369, Free PMC Article
    4. The meiosis-specific Cdc20 family-member Ama1 promotes binding of the Ssp2 activator to the Smk1 MAP kinase. Omerza G, et al. Mol Biol Cell, 2018 Jan 1. PMID 29118076, Free PMC Article
    5. Activation of the Smk1 mitogen-activated protein kinase by developmentally regulated autophosphorylation. Whinston E, et al. Mol Cell Biol, 2013 Feb. PMID 23207907, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ascospore formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ascospore wall assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of protein autophosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in ascospore wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in prospore membrane HDA PubMed 
    located_in spore wall IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ssp2p
    NP_014885.3
    • Sporulation specific protein that localizes to the spore wall; required for sporulation at a point after meiosis II and during spore wall formation; expression controlled by a tightly regulated middle-meiotic promoter that is activated by Ndt80p; translation of SSP2 mRNA is delayed, such that the mRNA is present as nuclear divisions are taking place but is not engaged by ribosomes until relatively late in meiotic development

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      788742..789857 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183661.3 → NP_014885.3  TPA: Ssp2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014885.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2U4, Q08646, Q96US5
      UniProtKB/TrEMBL
      C7GWE6, C8ZGZ4, N1P3I9
      Conserved Domains (2) summary
      cd12419
      Location:290 → 369
      RRM_Ssp2_like; RNA recognition motif (RRM) found in yeast sporulation-specific protein 2 (Ssp2) and similar protein
      cl17169
      Location:164 → 240
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08646.1

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