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    ERR1 phosphopyruvate hydratase ERR1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854575, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ERR1
    Official Full Name
    phosphopyruvate hydratase ERR1
    Primary source
    SGD:S000005920
    Locus tag
    YOR393W
    See related
    AllianceGenome:SGD:S000005920; FungiDB:YOR393W; VEuPathDB:YOR393W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable phosphopyruvate hydratase activity. Predicted to be involved in glycolytic process. Predicted to be part of phosphopyruvate hydratase complex. Human ortholog(s) of this gene implicated in Alzheimer's disease and prostate cancer. Orthologous to human ENO1 (enolase 1); ENO2 (enolase 2); and ENO3 (enolase 3). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See ERR1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (1080276..1081589)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene fluoride transporter Neighboring gene glutathione-independent methylglyoxalase family protein Neighboring gene seripauperin PAU21 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence analysis of the right end of chromosome XV in Saccharomyces cerevisiae: an insight into the structural and functional significance of sub-telomeric repeat sequences. Pryde FE, et al. Yeast, 1995 Apr 15. PMID 7785338
    2. Multiple knockout analysis of genetic robustness in the yeast metabolic network. Deutscher D, et al. Nat Genet, 2006 Sep. PMID 16941010
    3. The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. Dujon B, et al. Nature, 1997 May 29. PMID 9169874
    4. An integrated approach to characterize genetic interaction networks in yeast metabolism. Szappanos B, et al. Nat Genet, 2011 May 29. PMID 21623372, Free PMC Article
    5. Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. Mount HO, et al. PLoS Genet, 2018 Apr. PMID 29702647, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphopyruvate hydratase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphopyruvate hydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphopyruvate hydratase activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in glycolytic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glycolytic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    part_of phosphopyruvate hydratase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of phosphopyruvate hydratase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    phosphopyruvate hydratase ERR1
    NP_015038.1
    • Putative phosphopyruvate hydratase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      1080276..1081589
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183813.1 → NP_015038.1  TPA: phosphopyruvate hydratase ERR1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015038.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W385, P0CX10, P0CX11, Q12007, Q7LGJ4
      UniProtKB/TrEMBL
      A6ZVX7, B3LK45, B5VSR2, C7GSW8, C8ZHE0
      Conserved Domains (1) summary
      PTZ00081
      Location:1 → 428
      PTZ00081; enolase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CX10.1
    P0CX11.1

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