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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854463, updated on 2-Nov-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000005815
    Locus tag
    YOR289W
    See related
    AllianceGenome:SGD:S000005815; FungiDB:YOR289W; VEuPathDB:YOR289W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in midface hypoplasia, hearing impairment, elliptocytosis, and nephrocalcinosis. Orthologous to several human genes including AMMECR1L (AMMECR1 like). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (853357..854112)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene rRNA-processing protein RRP36 Neighboring gene protein disulfide isomerase MPD1 Neighboring gene tRNA-Ala Neighboring gene SWI/SNF catalytic subunit SNF2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. IRE1-independent gain control of the unfolded protein response. Leber JH, et al. PLoS Biol, 2004 Aug. PMID 15314654, Free PMC Article
    2. Deletion of EFL1 results in heterogeneity of the 60 S GTPase-associated rRNA conformation. Graindorge JS, et al. J Mol Biol, 2005 Sep 16. PMID 16095611
    3. Growth-Regulated Hsp70 Phosphorylation Regulates Stress Responses and Prion Maintenance. Kao CH, et al. Mol Cell Biol, 2020 May 28. PMID 32205407, Free PMC Article
    4. Yeast Saccharomyces cerevisiae adiponectin receptor homolog Izh2 is involved in the regulation of zinc, phospholipid and pH homeostasis. Mattiazzi Ušaj M, et al. Metallomics, 2015 Sep. PMID 26067383
    5. Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7. Logan MR, et al. BMC Genomics, 2008 Jul 15. PMID 18627629, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_014932.1
    • hypothetical protein; transcription induced by the unfolded protein response; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      853357..854112
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183708.1 → NP_014932.1  TPA: uncharacterized protein YOR289W [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014932.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2Y7, Q12012
      UniProtKB/TrEMBL
      A6ZPC4, B3LJV3, B5VSG6, C7GWA3, C8ZH39, G2WNF5, N1NWX4
      Conserved Domains (1) summary
      TIGR00296
      Location:12 → 251
      TIGR00296; uncharacterized protein, PH0010 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12012.1

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