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    Cdhr3 cadherin-related family member 3 [ Mus musculus (house mouse) ]

    Gene ID: 68764, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Cdhr3provided by MGI
    Official Full Name
    cadherin-related family member 3provided by MGI
    Primary source
    MGI:MGI:1916014
    See related
    Ensembl:ENSMUSG00000035860 AllianceGenome:MGI:1916014
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cdh28; 1110049B09Rik
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to be active in plasma membrane. Orthologous to human CDHR3 (cadherin related family member 3). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in lung adult (RPKM 4.3), ovary adult (RPKM 1.8) and 4 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Cdhr3 in Genome Data Viewer
    Location:
    12 A3; 12 13.95 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (33083781..33142900, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (33033795..33092901, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:33639684-33639867 Neighboring gene STARR-seq mESC enhancer starr_31885 Neighboring gene synaptophysin like 1 Neighboring gene predicted gene, 40874 Neighboring gene predicted gene, 24922 Neighboring gene RIKEN cDNA F730043M19 gene Neighboring gene STARR-seq mESC enhancer starr_31887 Neighboring gene ataxin 7-like 1 Neighboring gene predicted gene, 38649

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    cadherin-related family member 3
    Names
    cadherin-like protein 28

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024478.1 → NP_001019649.1  cadherin-related family member 3 precursor

      See identical proteins and their annotated locations for NP_001019649.1

      Status: PROVISIONAL

      Source sequence(s)
      AK047666, AK049806
      Consensus CDS
      CCDS36430.1
      UniProtKB/Swiss-Prot
      B2RSL6, Q8BL00
      Related
      ENSMUSP00000093449.3, ENSMUST00000095774.3
      Conserved Domains (1) summary
      cd11304
      Location:465 → 561
      Cadherin_repeat; Cadherin tandem repeat domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      33083781..33142900 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515190.5 → XP_006515253.1  cadherin-related family member 3 isoform X1

      See identical proteins and their annotated locations for XP_006515253.1

      UniProtKB/Swiss-Prot
      B2RSL6, Q8BL00
      Conserved Domains (1) summary
      cd11304
      Location:465 → 561
      Cadherin_repeat; Cadherin tandem repeat domain

    2. XM_011243893.3 → XP_011242195.1  cadherin-related family member 3 isoform X3

      Conserved Domains (1) summary
      cd11304
      Location:186 → 282
      Cadherin_repeat; Cadherin tandem repeat domain

    3. XM_011243894.3 → XP_011242196.1  cadherin-related family member 3 isoform X4

      Conserved Domains (1) summary
      cd11304
      Location:117 → 213
      Cadherin_repeat; Cadherin tandem repeat domain

    4. XM_036157603.1 → XP_036013496.1  cadherin-related family member 3 isoform X2

      Conserved Domains (1) summary
      cd11304
      Location:465 → 561
      Cadherin_repeat; Cadherin tandem repeat domain

    RNA

    1. XR_004937539.1 RNA Sequence

    2. XR_381204.5 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BL00.2 GenPept UniProtKB/Swiss-Prot:Q8BL00

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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