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    dod-19 Downstream Of DAF-16 (regulated by DAF-16);GH131_N domain-containing protein;IgGFc_binding domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178564, updated on 2-Nov-2024

    Summary

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    Official Symbol
    dod-19
    Official Full Name
    Downstream Of DAF-16 (regulated by DAF-16);GH131_N domain-containing protein;IgGFc_binding domain-containing protein
    Primary source
    WormBase:WBGene00022644
    Locus tag
    CELE_ZK6.10
    See related
    AllianceGenome:WB:WBGene00022644
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in innate immune response. Located in membrane raft. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See dod-19 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (411782..414759, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene CUB_2 domain-containing protein Neighboring gene UNC93-like protein MFSD11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans. Honda Y, et al. PLoS One, 2011. PMID 21858156, Free PMC Article
    2. Identification and characterization of differentially expressed genes in Caenorhabditis elegans in response to pathogenic and nonpathogenic Stenotrophomonas maltophilia. Radeke LJ, et al. BMC Microbiol, 2020 Jun 19. PMID 32560629, Free PMC Article
    3. ADAR-mediated regulation of PQM-1 expression in neurons impacts gene expression throughout C. elegans and regulates survival from hypoxia. Mahapatra A, et al. PLoS Biol, 2023 Sep. PMID 37747897, Free PMC Article
    4. Salmonella enterica serovar Paratyphi A-induced immune response in Caenorhabditis elegans depends on MAPK pathways and DAF-16. Ding AJ, et al. Front Immunol, 2023. PMID 37122724, Free PMC Article
    5. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop. Lee Y, et al. J Cell Biol, 2021 May 3. PMID 33666644, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in innate immune response HEP PubMed 
    Component Evidence Code Pubs
    located_in membrane raft HDA PubMed 

    General protein information

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    Preferred Names
    Downstream Of DAF-16 (regulated by DAF-16);GH131_N domain-containing protein;IgGFc_binding domain-containing protein
    NP_001300296.1
    • Confirmed by transcript evidence
    NP_001300297.1
    • Product from WormBase gene class dod;
      Confirmed by transcript evidence
    NP_503193.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      411782..414759 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070792.8 → NP_503193.1  IgGFc_binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503193.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O61874
      Conserved Domains (1) summary
      pfam03409
      Location:41 → 389
      Glycoprotein; Transmembrane glycoprotein

    2. NM_001313367.3 → NP_001300296.1  GH131_N domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AVF2
      Conserved Domains (1) summary
      pfam03409
      Location:4 → 236
      Glycoprotein; Transmembrane glycoprotein

    3. NM_001313368.3 → NP_001300297.1  Downstream Of DAF-16 (regulated by DAF-16) [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3ASK2
      Conserved Domains (1) summary
      pfam03409
      Location:9 → 40
      Glycoprotein; Transmembrane glycoprotein
    Nucleotide Protein
    Heading Accession and Version

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