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    Stpg1 sperm-tail PG-rich repeat containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500566, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Stpg1provided by RGD
    Official Full Name
    sperm-tail PG-rich repeat containing 1provided by RGD
    Primary source
    RGD:1560169
    See related
    EnsemblRapid:ENSRNOG00000031448 AllianceGenome:RGD:1560169
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mapo2
    Summary
    Predicted to be involved in positive regulation of apoptotic process and positive regulation of mitochondrial membrane permeability involved in apoptotic process. Predicted to be located in mitochondrion and nucleus. Orthologous to human STPG1 (sperm tail PG-rich repeat containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 23.7), Adrenal (RPKM 7.6) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Stpg1 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (153000663..153053391)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (147717084..147769792)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (153834263..153888510)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene noncompact myelin associated protein Neighboring gene uncharacterized LOC134487010 Neighboring gene RCAN family member 3 Neighboring gene NIPA-like domain containing 3 Neighboring gene microRNA 6333 Neighboring gene small nucleolar RNA SNORD104 Neighboring gene grainyhead-like transcription factor 3 Neighboring gene uncharacterized LOC134479040

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O⁶-methylguanine. Fujikane R, et al. PLoS One, 2012. PMID 23028632, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC114440

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of mitochondrial membrane permeability involved in apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of mitochondrial membrane permeability involved in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    O(6)-methylguanine-induced apoptosis 2
    Names
    O6-methylguanine-induced apoptosis 2
    UPF0490 protein C1orf201 homolog
    sperm-tail PG-rich repeat-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025772.1 → NP_001020943.1  O(6)-methylguanine-induced apoptosis 2

      See identical proteins and their annotated locations for NP_001020943.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098937
      UniProtKB/Swiss-Prot
      Q4KLY8
      UniProtKB/TrEMBL
      A6IT57, A6IT58
      Related
      ENSRNOP00000051024.3, ENSRNOT00000041600.5
      Conserved Domains (1) summary
      COG4916
      Location:5 → 111
      COG4916; Uncharacterized protein [Function unknown]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      153000663..153053391
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017593586.3 → XP_017449075.1  O(6)-methylguanine-induced apoptosis 2 isoform X1

      UniProtKB/Swiss-Prot
      Q4KLY8
      UniProtKB/TrEMBL
      A6IT57, A6IT58
      Conserved Domains (1) summary
      COG4916
      Location:5 → 111
      COG4916; Uncharacterized protein [Function unknown]

    2. XM_063288275.1 → XP_063144345.1  O(6)-methylguanine-induced apoptosis 2 isoform X8

    3. XM_017593587.3 → XP_017449076.1  O(6)-methylguanine-induced apoptosis 2 isoform X1

      UniProtKB/Swiss-Prot
      Q4KLY8
      UniProtKB/TrEMBL
      A6IT57, A6IT58
      Conserved Domains (1) summary
      COG4916
      Location:5 → 111
      COG4916; Uncharacterized protein [Function unknown]

    4. XM_063288272.1 → XP_063144342.1  O(6)-methylguanine-induced apoptosis 2 isoform X3

      Related
      ENSRNOP00000104091.1, ENSRNOT00000130605.1

    5. XM_063288273.1 → XP_063144343.1  O(6)-methylguanine-induced apoptosis 2 isoform X6

    6. XM_017593591.2 → XP_017449080.1  O(6)-methylguanine-induced apoptosis 2 isoform X4

      UniProtKB/TrEMBL
      A0A8L2R547
      Related
      ENSRNOP00000071989.2, ENSRNOT00000077610.3

    7. XM_063288274.1 → XP_063144344.1  O(6)-methylguanine-induced apoptosis 2 isoform X7

    8. XM_039110619.1 → XP_038966547.1  O(6)-methylguanine-induced apoptosis 2 isoform X8

    9. XM_039110621.2 → XP_038966549.1  O(6)-methylguanine-induced apoptosis 2 isoform X8

    10. XM_063288276.1 → XP_063144346.1  O(6)-methylguanine-induced apoptosis 2 isoform X8

    11. XM_017593589.3 → XP_017449078.1  O(6)-methylguanine-induced apoptosis 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZXI5
      Related
      ENSRNOP00000084555.1, ENSRNOT00000109048.2

    12. XM_039110618.2 → XP_038966546.1  O(6)-methylguanine-induced apoptosis 2 isoform X5

    13. XM_063288277.1 → XP_063144347.1  O(6)-methylguanine-induced apoptosis 2 isoform X8

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4KLY8.1 GenPept UniProtKB/Swiss-Prot:Q4KLY8

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