Cstf2t cleavage stimulation factor subunit 2, tau variant [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cstf2tprovided by RGD
Official Full Name: cleavage stimulation factor subunit 2, tau variantprovided by RGD
Primary source: RGD:1310026
See related: EnsemblRapid:ENSRNOG00000070422 AllianceGenome:RGD:1310026
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable mRNA binding activity. Predicted to be involved in mRNA 3'-end processing. Predicted to be located in nucleoplasm. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Orthologous to human CSTF2T (cleavage stimulation factor subunit 2 tau variant). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: 1q52

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (238366042..238369608)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (228952617..228956183)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (249574954..249578520)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	ISO Inferred from Sequence Orthology more info
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in mRNA 3'-end processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
part_of mRNA cleavage and polyadenylation specificity factor complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: cleavage stimulation factor subunit 2 tau variant

Names: cleavage stimulation factor subunit 2 tau; cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau; cleavage stimulation factor, 3' pre-RNA, subunit 2, tau

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107586.1 → NP_001101056.1 cleavage stimulation factor subunit 2 tau variant

See identical proteins and their annotated locations for NP_001101056.1

Status: PROVISIONAL

Source sequence(s)

CH473953

UniProtKB/TrEMBL

A6I0Z3, B5DFH8

Related

ENSRNOP00000105696.1, ENSRNOT00000160272.1

Conserved Domains (4) summary

COG0724
Location:16 → 109

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cd12671
Location:18 → 92

RRM_CSTF2_CSTF2T; RNA recognition motif in cleavage stimulation factor subunit 2 (CSTF2), cleavage stimulation factor subunit 2 tau variant (CSTF2T) and similar proteins

pfam14304
Location:585 → 625

CSTF_C; Transcription termination and cleavage factor C-terminal

pfam14327
Location:113 → 191

CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2