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    Eif2s3y eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100312984, updated on 2-Nov-2024

    Summary

    Symbol
    Eif2s3yprovided by RGD
    Full Name
    eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linkedprovided by RGD
    Primary source
    RGD:2314438
    See related
    EnsemblRapid:ENSRNOG00000060048 AllianceGenome:RGD:2314438
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable translation initiation factor activity. Predicted to contribute to tRNA binding activity. Predicted to be involved in formation of translation preinitiation complex. Predicted to be part of eukaryotic translation initiation factor 2 complex. Orthologous to human EIF2S3B (eukaryotic translation initiation factor 2 subunit gamma B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 217.4), Spleen (RPKM 211.1) and 8 other tissues See more
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    Genomic context

    See Eif2s3y in Genome Data Viewer
    Location:
    Yq11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) Y NC_086040.1 (944653..964303)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) Y NC_051357.1 (869654..889341)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) Y NC_024475.1 (914062..933699)

    Chromosome Y - NC_086040.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-like modifier-activating enzyme 1 Y Neighboring gene ubiquitin-like modifier-activating enzyme 1 Y Neighboring gene ubiquitin-conjugating enzyme E2 Q2 pseudogene Neighboring gene ubiquitously transcribed tetratricopeptide repeat containing, Y-linked Neighboring gene DEAD box helicase 3, Y-linked

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC187904

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to tRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables tRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in formation of translation preinitiation complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of eukaryotic translation initiation factor 2 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of eukaryotic translation initiation factor 2 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 2 subunit 3, Y-linked
    Names
    eIF-2-gamma Y
    eukaryotic translation initiation factor 2 subunit gamma, Y-linked
    eukaryotic translation initiation factor 2, subunit 3 gamma
    NP_001161138.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001167666.1NP_001161138.1  eukaryotic translation initiation factor 2 subunit 3, Y-linked

      See identical proteins and their annotated locations for NP_001161138.1

      Status: PROVISIONAL

      Source sequence(s)
      BC158736
      UniProtKB/Swiss-Prot
      A0A096MIV4, A0A0G2JU42, C9WPN6, C9WPN7, W8CEN7
      UniProtKB/TrEMBL
      A0A8L2R4R9
      Related
      ENSRNOP00000068958.2, ENSRNOT00000088593.4
      Conserved Domains (1) summary
      PTZ00327
      Location:13466
      PTZ00327; eukaryotic translation initiation factor 2 gamma subunit; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086040.1 Reference GRCr8

      Range
      944653..964303
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)