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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001303034.2 → NP_001289963.1 neuronal acetylcholine receptor subunit alpha-10 isoform b
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site at an internal exon compared to variant 1. This difference results in translation initiation at a downstream in-frame start site through ribosomal re-initiation or leaky scanning. The encoded isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
- Source sequence(s)
-
AC060812, AF199235, BC143303
- UniProtKB/Swiss-Prot
-
Q9GZZ6
- Conserved Domains (2) summary
-
- pfam02931
Location:1 → 29
- Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
- pfam02932
Location:37 → 228
- Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
-
NM_001303035.2 → NP_001289964.1 neuronal acetylcholine receptor subunit alpha-10 isoform b
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) uses two alternate splice sites at an internal exon compared to variant 1. These differences result in translation initiation at a downstream in-frame start site through ribosomal re-initiation or leaky scanning. The encoded isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
- Source sequence(s)
-
AC060812, AF199235, BC136250
- UniProtKB/Swiss-Prot
-
Q9GZZ6
- UniProtKB/TrEMBL
-
C4IXS7
- Conserved Domains (2) summary
-
- pfam02931
Location:1 → 29
- Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
- pfam02932
Location:37 → 228
- Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
-
NM_020402.4 → NP_065135.2 neuronal acetylcholine receptor subunit alpha-10 isoform a precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (a).
- Source sequence(s)
-
AC060812, AF199235
- Consensus CDS
-
CCDS7745.1
- UniProtKB/Swiss-Prot
-
Q9GZZ6
- UniProtKB/TrEMBL
-
C4IXS7
- Related
- ENSP00000250699.2, ENST00000250699.2
- Conserved Domains (3) summary
-
- TIGR00860
Location:31 → 442
- LIC; Cation transporter family protein
- pfam02931
Location:32 → 235
- Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
- pfam02932
Location:243 → 434
- Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000011.10 Reference GRCh38.p14 Primary Assembly
- Range
-
3665587..3671384 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060935.1 Alternate T2T-CHM13v2.0
- Range
-
3730960..3736757 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)