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    Samd14 sterile alpha motif domain containing 14 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287637, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Samd14provided by RGD
    Official Full Name
    sterile alpha motif domain containing 14provided by RGD
    Primary source
    RGD:1306138
    See related
    EnsemblRapid:ENSRNOG00000004155 AllianceGenome:RGD:1306138
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306138
    Summary
    Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization; calcium-mediated signaling; and neuron projection development. Predicted to be active in several cellular components, including actin cytoskeleton; dendrite; and postsynaptic density. Orthologous to human SAMD14 (sterile alpha motif domain containing 14). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 31.4), Kidney (RPKM 4.2) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Samd14 in Genome Data Viewer
    Location:
    10q26
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (80453952..80469182)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (79957111..79972347)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (82820457..82838046)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene sarcoglycan, alpha Neighboring gene uncharacterized LOC102557019 Neighboring gene protein phosphatase 1, regulatory subunit 9B Neighboring gene uncharacterized LOC120095177 Neighboring gene pyruvate dehydrogenase kinase 2 Neighboring gene integrin subunit alpha 3 Neighboring gene uncharacterized LOC102546327

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Structural Analysis of Hippocampal Kinase Signal Transduction. McClatchy DB, et al. ACS Chem Neurosci, 2018 Dec 19. PMID 30053369, Free PMC Article
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC109312

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in calcium-mediated signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in postsynaptic density IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    sterile alpha motif domain-containing protein 14
    Names
    SAM domain-containing protein 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024966.1 → NP_001020137.1  sterile alpha motif domain-containing protein 14

      See identical proteins and their annotated locations for NP_001020137.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091329
      UniProtKB/Swiss-Prot
      Q5BJU3
      UniProtKB/TrEMBL
      A0A8I6AB96
      Related
      ENSRNOP00000102189.1, ENSRNOT00000123741.1
      Conserved Domains (2) summary
      cd09512
      Location:321 → 386
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      smart00454
      Location:323 → 386
      SAM; Sterile alpha motif

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      80453952..80469182
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039085587.2 → XP_038941515.1  sterile alpha motif domain-containing protein 14 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AB96, F1LN57
      Related
      ENSRNOP00000005519.8, ENSRNOT00000005519.9
      Conserved Domains (2) summary
      cd09512
      Location:323 → 388
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
      PHA03307
      Location:45 → 236
      PHA03307; transcriptional regulator ICP4; Provisional

    2. XM_039085588.2 → XP_038941516.1  sterile alpha motif domain-containing protein 14 isoform X2

      UniProtKB/TrEMBL
      A6HI78
      Conserved Domains (1) summary
      cd09512
      Location:309 → 374
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily

    3. XM_039085589.2 → XP_038941517.1  sterile alpha motif domain-containing protein 14 isoform X3

      UniProtKB/TrEMBL
      A0A8I6AB96
      Conserved Domains (1) summary
      cd09512
      Location:255 → 320
      SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BJU3.1 GenPept UniProtKB/Swiss-Prot:Q5BJU3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
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