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    Sypl2 synaptophysin-like 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362018, updated on 2-Nov-2024

    Summary

    Official Symbol
    Sypl2provided by RGD
    Official Full Name
    synaptophysin-like 2provided by RGD
    Primary source
    RGD:1309907
    See related
    EnsemblRapid:ENSRNOG00000019780 AllianceGenome:RGD:1309907
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mg29
    Summary
    Predicted to be involved in substantia nigra development. Predicted to act upstream of or within T-tubule organization; heart development; and intracellular calcium ion homeostasis. Predicted to be active in synaptic vesicle membrane. Orthologous to human SYPL2 (synaptophysin like 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 564.2) See more
    Orthologs
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    Genomic context

    See Sypl2 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (198537208..198551939, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (195849062..195863794, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (211003046..211017778, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene cytochrome b561 family, member D1 Neighboring gene ataxin 7-like 2 Neighboring gene uncharacterized LOC134485671 Neighboring gene proteasome 20S subunit alpha 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    synaptophysin-like protein 2
    Names
    mitsugumin29

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108563.1NP_001102033.1  synaptophysin-like protein 2

      See identical proteins and their annotated locations for NP_001102033.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473952
      UniProtKB/TrEMBL
      A6HUY9, D4A6M0
      Related
      ENSRNOP00000026883.2, ENSRNOT00000026883.5
      Conserved Domains (1) summary
      pfam01284
      Location:30232
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      198537208..198551939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)