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    TIP1 putative lipase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852359, updated on 28-Oct-2024

    Summary

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    Official Symbol
    TIP1
    Official Full Name
    putative lipase
    Primary source
    SGD:S000000271
    Locus tag
    YBR067C
    See related
    AllianceGenome:SGD:S000000271; FungiDB:YBR067C; VEuPathDB:YBR067C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables lipase activity. A structural constituent of cell wall. Involved in fungal-type cell wall organization. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

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    See TIP1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (372103..372735, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Ecm2p Neighboring gene Nrg2p Neighboring gene branched-chain amino acid permease BAP2 Neighboring gene amino acid transporter TAT1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TIP 1, a cold shock-inducible gene of Saccharomyces cerevisiae. Kondo K, et al. J Biol Chem, 1991 Sep 15. PMID 1894636
    2. Structure of the glucan-binding sugar chain of Tip1p, a cell wall protein of Saccharomyces cerevisiae. Fujii T, et al. Biochim Biophys Acta, 1999 Apr 19. PMID 10216230
    3. Characterization and isolation of mutants producing increased amounts of isoamyl acetate derived from hygromycin B-resistant sake yeast. Inoue T, et al. Biosci Biotechnol Biochem, 2012. PMID 22232249
    4. Identification of cis- and trans-acting elements involved in the expression of cold shock-inducible TIP1 gene of yeast Saccharomyces cerevisiae. Muñoz-Dorado J, et al. Nucleic Acids Res, 1994 Feb 25. PMID 8127704, Free PMC Article
    5. A novel esterase from Saccharomyces carlsbergensis, a possible function for the yeast TIP1 gene. Horsted MW, et al. Yeast, 1998 Jun 30. PMID 9818717

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fungal-type cell wall organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in cytosol HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in fungal-type cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative lipase
    NP_009623.1
    • Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      372103..372735 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178415.1 → NP_009623.1  TPA: putative lipase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009623.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQ66, P27654
      UniProtKB/TrEMBL
      C7GQI2, G2W972, N1P822
      Conserved Domains (1) summary
      pfam00660
      Location:15 → 108
      SRP1_TIP1; Seripauperin and TIP1 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P27654.1

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