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    Rnf223 ring finger protein 223 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680874, updated on 2-Nov-2024

    Summary

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    Symbol
    Rnf223provided by RGD
    Full Name
    ring finger protein 223provided by RGD
    Primary source
    RGD:1587009
    See related
    EnsemblRapid:ENSRNOG00000036856 AllianceGenome:RGD:1587009
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable metal ion binding activity. Predicted to be located in membrane. Orthologous to human RNF223 (ring finger protein 223). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 10.3), Thymus (RPKM 10.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rnf223 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (172005566..172008456)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (166723346..166726236)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (173561016..173566844)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene tubulin tyrosine ligase like 10 Neighboring gene uncharacterized LOC106182250 Neighboring gene microRNA 200b Neighboring gene similar to human chromosome 1 open reading frame 159 Neighboring gene single-stranded DNA binding protein 2, pseudogene 1 Neighboring gene agrin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • AC097183.1

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RING finger protein 223

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398967.1 → NP_001385896.1  RING finger protein 223

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A8I5Y6Y6
      Related
      ENSRNOP00000109675.1, ENSRNOT00000158718.1
      Conserved Domains (1) summary
      cd16556
      Location:50 → 105
      RING-HC_RNF183_like; RING finger, HC subclass, found in RING finger protein RNF183, RNF223 and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      172005566..172008456
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039111398.2 → XP_038967326.1  RING finger protein 223 isoform X1

      Related
      ENSRNOP00000077995.2, ENSRNOT00000055314.6
      Conserved Domains (1) summary
      cd16556
      Location:54 → 109
      RING-HC_RNF183_like; RING finger, HC subclass, found in RING finger protein RNF183, RNF223 and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials