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    tho4 THO complex subunit [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540184, updated on 18-Sep-2024

    Summary

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    Official Symbol
    tho4
    Official Full Name
    THO complex subunit
    Primary source
    PomBase:SPBC106.12c
    Locus tag
    SPOM_SPBC106.12C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See tho4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003423.3 (400954..402365, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene cAMP-dependent protein kinase catalytic subunit Pka1 Neighboring gene ncRNA Neighboring gene 1-alkyl-2-acetylglycerophosphocholine esterase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin ligase complex subunit Neighboring gene SDA1 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Red5 and three nuclear pore components are essential for efficient suppression of specific mRNAs during vegetative growth of fission yeast. Sugiyama T, et al. Nucleic Acids Res, 2013 Jul. PMID 23658229, Free PMC Article
    2. Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA. Zhang K, et al. Science, 2011 Mar 25. PMID 21436456, Free PMC Article
    3. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in poly(A)+ mRNA export from nucleus IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of THO complex part of transcription export complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    THO complex subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      400954..402365 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021070.3 → NP_595161.1  THO complex subunit [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595161.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9URV0
      Conserved Domains (2) summary
      COG0724
      Location:1 → 229
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12418
      Location:87 → 158
      RRM_Aly_REF_like; RNA recognition motif in the Aly/REF family
    Nucleotide Protein
    Heading Accession and Version

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