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    zng1 nucleotide-binding domain-containing protein CobW/HypB/UreG [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539606, updated on 18-Sep-2024

    Summary

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    Official Symbol
    zng1
    Official Full Name
    nucleotide-binding domain-containing protein CobW/HypB/UreG
    Primary source
    PomBase:SPBC15D4.05
    Locus tag
    SPOM_SPBC15D4.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See zng1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3020681..3022237)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene histone H3.3-H4 chaperone, HIR complex WD repeat subunit Hip2 Neighboring gene UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene NatC N-acetyltransferase complex catalytic subunit Naa30 Neighboring gene autophagy-associated protein Atg9 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Zng1 is a GTP-dependent zinc transferase needed for activation of methionine aminopeptidase. Pasquini M, et al. Cell Rep, 2022 May 17. PMID 35584675
    2. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    3. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTPase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables zinc ion binding IC
    Inferred by Curator
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular zinc ion homeostasis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    nucleotide-binding domain-containing protein CobW/HypB/UreG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3020681..3022237
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022164.2 → NP_596245.1  nucleotide-binding domain-containing protein CobW/HypB/UreG [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596245.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74310
      Conserved Domains (3) summary
      smart00833
      Location:307 → 402
      CobW_C; Cobalamin synthesis protein cobW C-terminal domain
      COG0523
      Location:61 → 402
      YejR; GTPase, G3E family [General function prediction only]
      pfam02492
      Location:62 → 246
      cobW; CobW/HypB/UreG, nucleotide-binding domain
    Nucleotide Protein
    Heading Accession and Version

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