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    DAN4 Dan4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853616, updated on 17-May-2024

    Summary

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    Gene symbol
    DAN4
    Gene description
    Dan4p
    Primary source
    FungiDB:YJR151C
    Locus tag
    YJR151C
    See related
    SGD:S000003912; AllianceGenome:SGD:S000003912
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be a structural constituent of cell wall. Predicted to be involved in fungal-type cell wall organization. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See DAN4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (712255..715740, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene putative nitronate monooxygenase Neighboring gene Dan1p Neighboring gene uncharacterized protein Neighboring gene allantoate permease

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The DAN1 gene of S. cerevisiae is regulated in parallel with the hypoxic genes, but by a different mechanism. Sertil O, et al. Gene, 1997 Jun 19. PMID 9224891
    2. Deletion of new covalently linked cell wall glycoproteins alters the electrophoretic mobility of phosphorylated wall components of Saccharomyces cerevisiae. Mrsa V, et al. J Bacteriol, 1999 May. PMID 10322008, Free PMC Article
    3. Amino acid sequence requirement for efficient incorporation of glycosylphosphatidylinositol-associated proteins into the cell wall of Saccharomyces cerevisiae. Hamada K, et al. J Biol Chem, 1998 Oct 9. PMID 9756943
    4. Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene expression in Saccharomyces cerevisiae. Abramova N, et al. J Bacteriol, 2001 May. PMID 11292809, Free PMC Article
    5. Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins. Hamada K, et al. J Bacteriol, 1999 Jul. PMID 10383953, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables structural constituent of cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in fungal-type cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Dan4p
    NP_012685.1
    • Cell wall mannoprotein; has similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      712255..715740 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181809.2 → NP_012685.1  TPA: Dan4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012685.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWW9, P47179
      UniProtKB/TrEMBL
      A0A8H4BZW4
      Conserved Domains (2) summary
      pfam00660
      Location:28 → 117
      SRP1_TIP1; Seripauperin and TIP1 family
      NF033849
      Location:397 → 670
      ser_rich_anae_1; serine-rich protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47179.1

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