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    HBT1 Hbt1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851303, updated on 29-Jun-2024

    Summary

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    Gene symbol
    HBT1
    Gene description
    Hbt1p
    Primary source
    FungiDB:YDL223C
    Locus tag
    YDL223C
    See related
    SGD:S000002382; AllianceGenome:SGD:S000002382; VEuPathDB:YDL223C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in cell morphogenesis involved in conjugation with cellular fusion. Located in mating projection. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See HBT1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (57265..60405, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene septin SHS1 Neighboring gene Whi4p Neighboring gene Fmp45p Neighboring gene telomere-binding protein CDC13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of a ubiquitin-like modification in polarized morphogenesis. Dittmar GA, et al. Science, 2002 Mar 29. PMID 11923536
    2. Identification of an Hsp90 mutation that selectively disrupts cAMP/PKA signaling in Saccharomyces cerevisiae. Flom GA, et al. Curr Genet, 2012 Jun. PMID 22461145
    3. Genomic analysis of stationary-phase and exit in Saccharomyces cerevisiae: gene expression and identification of novel essential genes. Martinez MJ, et al. Mol Biol Cell, 2004 Dec. PMID 15456898, Free PMC Article
    4. The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock. Garre E, et al. PLoS Genet, 2018 Jul. PMID 30059503, Free PMC Article
    5. Dbf4-dependent CDC7 kinase links DNA replication to the segregation of homologous chromosomes in meiosis I. Matos J, et al. Cell, 2008 Nov 14. PMID 19013276

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell morphogenesis involved in conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mating projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    Hbt1p
    NP_010058.1
    • Shmoo tip protein, substrate of Hub1p ubiquitin-like protein; mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis; HBT1 has a paralog, YNL195C, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      57265..60405 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180283.1 → NP_010058.1  TPA: Hbt1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010058.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRD2, Q07653
      UniProtKB/TrEMBL
      A0A8H8UM80, C7GSV5, C8Z6P6, N1P7W2
      Conserved Domains (1) summary
      NF033849
      Location:168 → 343
      ser_rich_anae_1; serine-rich protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q07653.1

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